A Retrospective Study to Characterize Patients With HER2-positive Metastatic or Locally Advanced Breast Cancer, Treated by Herceptin® as 1st Line-therapy and Without Progression for at Least 3 Years Followed by a 1-year Prospective Study for Patients Stil

{"level_sex_clusion_I":[{"value":"Female","concept":{"vocab":"MeSH","vocabURI":"D005260"}}],"level_age_clusion_I":[{"value":"Young Adult (19 to 24 years)","concept":{"vocab":"MeSH","vocabURI":"D055815"}},{"value":"Adult (25 to 44 years)","concept":{"vocab":"MeSH","vocabURI":"D000328"}},{"value":"Middle Aged (45 to 64 years)","concept":{"vocab":"MeSH","vocabURI":"D008875"}},{"value":"Aged (65 to 79 years)","concept":{"vocab":"MeSH","vocabURI":"D000368"}},{"value":"Aged, 80 and over (80 years and more)","concept":{"vocab":"MeSH","vocabURI":"D000369"}}],"level_type_clusion_I":"Patients population","level_type_clusion_other":"","clusion_I":"Inclusion criteria: - Woman >= 18 years; - With HER2-positive metastatic breast cancer or locally-advanced breast cancer; - Treated with trastuzumab as first-line therapy; - Without progression for at least 3 years after initiation of trastuzumab treatment; - Alive or not alive, and treated or not treated with trastuzumab at the time of inclusion; For patients alive at the time of inclusion: - Having been informed orally and in writing about the study and having given their written consent to the automatic processing of her personal data and their consultation by a duly authorized third party; - For the patients who accepted the centralized histological analysis of their primitive tumor, a written consent. ","clusion_E":"Disease progression <3 years after beginning 1st-line therapy with Herceptin."}