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Observational, retrospective study exploring RAS mutation tests practices in patients with metastatic colorectal cancer in 2014

France, 2014
Reference ID
FRESH-PEF73329-en
Producer(s)
Pierre;LAURENT-PUIG, Astrid;LIEVRE, Jean-Louis;MERLIN, Jean-Christophe;SABOURIN, Pascal;ARTRU, Michel;DUCREUX
Metadata
DDI/XML JSON
Study website Interactive tools
Created on
Feb 18, 2026
Last modified
Feb 18, 2026
Page views
43
  • Study Description
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  • Identification
  • Scope
  • Coverage
  • Producers and sponsors
  • Study authorization
  • Sampling
  • Survey instrument
  • Data collection
  • Study activities
  • Data Access
  • Identification

    Survey ID number

    FRESH-PEF73329-en

    Title

    Observational, retrospective study exploring RAS mutation tests practices in patients with metastatic colorectal cancer in 2014

    Abbreviation or Acronym

    Flash-RAS

    Country
    Name Country code
    France fr
    Kind of Data

    ['Clinical data','Biological data','Participant-reported health data']

    Unit of Analysis

    Individuals

    Scope

    Topics
    Topic Vocabulary
    Oncology health theme
    Neoplasms cim-11
    Healthcare system determinants: Access to care health determinant
    Keywords
    RAS mutation tests Colorectal cancer

    Coverage

    Universe

    {"level_sex_clusion_I":[{"value":"Male","concept":{"vocab":"MeSH","vocabURI":"D008297"}},{"value":"Female","concept":{"vocab":"MeSH","vocabURI":"D005260"}}],"level_age_clusion_I":[{"value":"Young Adult (19 to 24 years)","concept":{"vocab":"MeSH","vocabURI":"D055815"}},{"value":"Adult (25 to 44 years)","concept":{"vocab":"MeSH","vocabURI":"D000328"}},{"value":"Middle Aged (45 to 64 years)","concept":{"vocab":"MeSH","vocabURI":"D008875"}},{"value":"Aged (65 to 79 years)","concept":{"vocab":"MeSH","vocabURI":"D000368"}},{"value":"Aged, 80 and over (80 years and more)","concept":{"vocab":"MeSH","vocabURI":"D000369"}}],"level_type_clusion_I":"Patients population","level_type_clusion_other":"","clusion_I":"To obtain the best possible representativeness while limiting bias, the physician had to screen consecutive patients followed for metastatic colorectal cancer and who had to satisfy the following criteria: - patients 18 years of age or older, - patients with metastatic colorectal cancer histologically-confirmed after march 2014 (date the NRAS tests become available in French centers), - patients seen by the physician between June 15th , 2014 and September 30th, 2014 who have already started first-line treatment, during that time interval, for mCRC - patients in whom first-line therapy of metastatic disease had been already initiated between March 1st, 2014 and June 30th, 2014 - patients seen in a routine visit during the official 15-week screening period of the study","clusion_E":""}

    Producers and sponsors

    Primary investigators
    Name
    Pierre;LAURENT-PUIG
    Astrid;LIEVRE
    Jean-Louis;MERLIN
    Jean-Christophe;SABOURIN
    Pascal;ARTRU
    Michel;DUCREUX
    Producers
    Name Role
    MERCK SANTE sponsor
    Funding Agency/Sponsor
    Name
    MERCK SANTE

    Study authorization

    Agency
    Agency name
    CNIL

    Sampling

    Sample frame

    Unit Type

    ['Through organizations (health services or institutions, schools, businesses, etc.)','Through independent healthcare practitioners']

    Sampling Procedure

    ['{"concept":{"vocabURI":"Other","vocab":"CESSDA"},"value":"Other"}']

    Survey instrument

    Questionnaires

    Access on specific project only

    Methodology notes

    Observational Study

    Data collection

    Dates of Data Collection
    Start End
    2014-01-01 2014-12-31
    Mode of data collection
    • {"concept":{"vocabURI":"Interview","vocab":"CESSDA"},"value":"Interview with the participant (including clinical)"}

    Study activities

    Study activities
    Study activities
    Type
    primary evaluation
    Description
    Health care consumption and services

    Data Access

    Availability Status

    {"value":"To be defined","extLink":[]}

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