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Cohort of Elderly Patients with T2D. Comparing the Risk of Hypoglycaemia in DPP4-Inhibitors (iDPP4) with Conventional Oral Antidiabetic Drugs as Add-On Therapy to Metformin.

France, 2009 - 2011
Reference ID
FRESH-PEF73265-en
Producer(s)
Isabelle;BOURDEL-MARCHASSON, Alfred;PENFORNIS, Sylvie;DEJAGER
Metadata
DDI/XML JSON
Study website Interactive tools
Created on
Feb 18, 2026
Last modified
Feb 18, 2026
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41
  • Study Description
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  • Identification
  • Scope
  • Coverage
  • Producers and sponsors
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  • Sampling
  • Survey instrument
  • Data collection
  • Study activities
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  • Contacts
  • Identification

    Survey ID number

    FRESH-PEF73265-en

    Title

    Cohort of Elderly Patients with T2D. Comparing the Risk of Hypoglycaemia in DPP4-Inhibitors (iDPP4) with Conventional Oral Antidiabetic Drugs as Add-On Therapy to Metformin.

    Abbreviation or Acronym

    HYPOCRAS

    Country
    Name Country code
    France fr
    Kind of Data

    ['Clinical data']

    Unit of Analysis

    Individuals

    Scope

    Topics
    Topic Vocabulary
    Endocrinology health theme
    Type 2 diabetes mellitus cim-11
    Healthcare system determinants: Use of care health determinant
    Behavioral determinants: Eating habits health determinant
    Healthcare system determinants: Access to care health determinant
    Healthcare system determinants health determinant
    Behavioral determinants health determinant
    Keywords
    type 2 diabetes elderly subject DPP4 inhibitors oral antidiabetic drugs hypoglycaemia

    Coverage

    Universe

    {"level_sex_clusion_I":[{"value":"Male","concept":{"vocab":"MeSH","vocabURI":"D008297"}},{"value":"Female","concept":{"vocab":"MeSH","vocabURI":"D005260"}}],"level_age_clusion_I":[{"value":"Aged (65 to 79 years)","concept":{"vocab":"MeSH","vocabURI":"D000368"}},{"value":"Aged, 80 and over (80 years and more)","concept":{"vocab":"MeSH","vocabURI":"D000369"}}],"level_type_clusion_I":"Patients population","level_type_clusion_other":"","clusion_I":"Patients eligible for the study were men and women of 65 years of age or over with T2D and HbA1c: ≥6.5% after a course of at least 3 months of metformin alone at a stable, maximum tolerated daily dose, requiring the prescription of a second OAD. Patients who had at least two follow-up visits planned over the next 6 months (± 1 month, 3 months, 6 months ± 1 month).","clusion_E":""}

    Producers and sponsors

    Primary investigators
    Name
    Isabelle;BOURDEL-MARCHASSON
    Alfred;PENFORNIS
    Sylvie;DEJAGER
    Producers
    Name Role
    CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX sponsor
    NOVARTIS PHARMA SAS sponsor
    CHU BESANCON (CHU) sponsor
    Funding Agency/Sponsor
    Name
    NOVARTIS PHARMA SAS

    Study authorization

    Agency
    Agency name
    CNIL

    Sampling

    Sample frame

    Unit Type

    ['Through independent healthcare practitioners']

    Sampling Procedure

    ['{"concept":{"vocabURI":"Other","vocab":"CESSDA"},"value":"Other"}']

    Survey instrument

    Questionnaires

    Access on specific project only

    Methodology notes

    Observational Study

    Data collection

    Dates of Data Collection
    Start End
    2009-01-01 2011-01-01
    Mode of data collection
    • {"concept":{"vocabURI":"Other","vocab":"CESSDA"},"value":"Other"}

    Study activities

    Study activities
    Study activities
    Type
    primary evaluation
    Description
    Health care consumption and services

    Data Access

    Access conditions

    Contact the principal investigator

    Availability Status

    {"value":"Restricted access","extLink":[{"title":"COAR","uri":"http://purl.org/coar/access_right/c_16ec"}]}

    Contacts

    Contacts
    Name Email
    Isabelle;BOURDEL-MARCHASSON Isabelle.bourdel-marchasson@chu-bordeaux.fr
    Alfred;PENFORNIS alfred.penfornis@chsf.fr
    Sylvie;DEJAGER sylvie.dejager@aphp.fr
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