Evaluation of targeted therapies in patients receiving first-line treatment for metastatic colorectal cancer: cetuximab in the real-life conditions of use

{"level_sex_clusion_I":[{"value":"Male","concept":{"vocab":"MeSH","vocabURI":"D008297"}},{"value":"Female","concept":{"vocab":"MeSH","vocabURI":"D005260"}}],"level_age_clusion_I":[{"value":"Young Adult (19 to 24 years)","concept":{"vocab":"MeSH","vocabURI":"D055815"}},{"value":"Adult (25 to 44 years)","concept":{"vocab":"MeSH","vocabURI":"D000328"}},{"value":"Middle Aged (45 to 64 years)","concept":{"vocab":"MeSH","vocabURI":"D008875"}},{"value":"Aged (65 to 79 years)","concept":{"vocab":"MeSH","vocabURI":"D000368"}},{"value":"Aged, 80 and over (80 years and more)","concept":{"vocab":"MeSH","vocabURI":"D000369"}}],"level_type_clusion_I":"Patients population","level_type_clusion_other":"","clusion_I":"Patient with metastatic colorectal cancer initiating first-line treatment with cetuximab® between 1 January 2009 and 31 December 2010, whether or not treatment is continued; Patient not previously treated by cetuximab®, including during a clinical trial or Temporary Authorisation for Use; Patient naive to palliative metastatic chemotherapyd; No neoadjuvant chemotherapy / adjuvant of primary cancer or interval between the latter and the initiation of first-line treatment with cetuximab® ≥6 months (with a tolerance of 15 days); No neoadjuvant / adjuvant of chemotherapy for metastatic cancer between or interval between the latter and initiation of first-line treatment with cetuximab® ≥12 months (with a tolerance of 1 month ); Patient with unresectable metastases immediately before initiation of cetuximab®; Patient with non-mutated K-RAS; Patient not participating in a clinical trial or treatment conditions considered to be unaffected by the coordinating center; Patient without locoregional relapse; Patient not objecting to data collection.","clusion_E":""}