Cohort on Predictive Exacerbation Factors in Severe Asthmatics FRESH-PEF8817-en Antoine MAGNAN Cohort on Predictive Exacerbation Factors in Severe Asthmatics EXPRESA - EXacerbation PREdictive factors in Severe Asthma FRESH-PEF8817-en 8817 FRESH-PEF8817 Antoine MAGNAN INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES Epidemiology France Portal (PEF) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES null Antoine;MAGNAN marker lymphocyte population predictive factors Allergology Asthma Healthcare system determinants: Use of care Biological determinants: Genetic predisposition Healthcare system determinants Biological determinants To validate exacerbation prediction in certain lymphocyte populations by comparing markers already identified (NO, EEI), based on factors that do or do not cause infection. null France Pays de la Loire Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Male and female; - Adult; - Severe asthmatic. Clinical data Participant-reported health data Health event/morbidity Other Through organizations (health services or institutions schools businesses etc.) < 500 individuals Interview with the participant (including clinical) Observational Study Observational Study Cohort study 45 Unknown Restricted access Contact the principal investigator Access on specific project only