Prevalence of Transthyretin Amyloidosis in Hypertrophic Cardiomyopathy FRESH-PEF8655-en Geneviève MULAK Prevalence of Transthyretin Amyloidosis in Hypertrophic Cardiomyopathy AMYLO-STUDY FRESH-PEF8655-en 8655 FRESH-PEF8655 Thibaud DAMY Violaine PLANTE-BORDENEUVE Michel SLAMA ASSOCIATION DE SOUTIEN A LA FILIALE D&#039;IMAGERIE CARDIOVASCULAIRE DE LA SOCIETE FRANCAISE DE CARDIOLOGIE (ASFIC) Epidemiology France Portal (PEF) ASSOCIATION DE SOUTIEN A LA FILIALE D&#039;IMAGERIE CARDIOVASCULAIRE DE LA SOCIETE FRANCAISE DE CARDIOLOGIE (ASFIC) null Thibaud;DAMY Violaine;PLANTE-BORDENEUVE Michel;SLAMA heredity under-diagnosis mutation prevalence Cardiology and vascular medicine Amyloidosis Biological determinants: Genetic predisposition Biological determinants To define the prevalence of TTR amyloidosis in a large population of patients attending the CMH. null France Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) Aged 18 years and over; - Cardiomyopathy defined by an ultrasound thickness of the left ventricle greater than or equal to13 mm if familial form, or greater than or equal to 15 mm if sporadic form; - Patients with a signed consent authorising the specific blood test for genetic sequencing to look for an abnormal TTR gene. Significant AS (less than or equal to 1cm2); - Patients with a cardiomyopathy diagnosis (sarcomeric HCM, Fabry disease, etc.) or related already diagnosed.Patients included in the REMY registry (Hypertrophic Cardiomyopathy Registry) may also be included in the amyloid-STUDY. Inclusion criteria are very similar. Some additional data will need to be completed on the page corresponding to the registry. Clinical data Participant-reported health data Biological data Paraclinical data (non-biological) : Imaging Paraclinical data (non-biological) : Function testing Health event/morbidity Health event/mortality One-time cross-sectional study Other Through organizations (health services or institutions schools businesses etc.) < 500 individuals Converting or copying information into a structured record Observational Study Observational Study Objective:260. 298 patients enrolled on 30/04/2014. Unknown Restricted access Contact the principal investigator Access on specific project only