«The assessment of EMDR* to treat post-traumatic-stress-disorder » Involvement of corticotropic and sympathetic axes. FRESH-PEF8571-en ISABELLE CHAUDIEU «The assessment of EMDR* to treat post-traumatic-stress-disorder » Involvement of corticotropic and sympathetic axes. EVEREST FRESH-PEF8571-en 8571 FRESH-PEF8571 Isabelle CHAUDIEU INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER (CHU) Epidemiology France Portal (PEF) MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES null Isabelle;CHAUDIEU Prospective study psychiatry naturalistic study EMDR psychotherapy assessment biological markers corticotropic and sympathetic axes salivary cortisol metabolic marker heart rate cutaneous conductance randomized study multicenter study psychiatric comorbidities. Post traumatic stress disorder PTSD clinical research allostatic load Endocrinology Psychiatry The main objective is to compare the effectiveness of EMDR psychotherapy and a supportive psychotherapy in chronic post-traumatic stress disorder patients, through a pragmatic-trial based on a daily practice of a psychiatry sector. Secondary objectives are 1)To study the link between diurnal salivary cortisol secretion and post traumatic symptoms 11)Over all the participants in the survey both at the inclusion and the 3 months visits 12)Over all the EMDR group participants, one year after the beginning of the cares. 2)To study the link between salivary cortisol levels during the EMDR sessions and post traumatic symptoms at 3 months (group 1) 3)To study the link between neurovegetative excitation regulation during the EMDR sessions and post traumatic symptoms at 3 months (group 1) 4)To assess the EMDR psychotherapy effect on a midterm, one year after the first EMDR session. null France Occitanie Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Women and men aged 18-75 years - Chronical PTSD patients (for more than 3 months, diagnosed by the CAPS scale/DSM IV criteria - Patients who are not following a psychotherapy focused on PTSD - Patients that never have followedr a CBT (Cognitive behavioral therapy) or a EMDR psychotherapy focused on the traumatic memory - Patients without psychotropic treatment or who have a stabilized treatment for at least 3 months. Clinical data Participant-reported health data Biological data DSM IV Health event/morbidity Health care consumption and services Others Other Through organizations (health services or institutions schools businesses etc.) < 500 individuals Self-administered questionnaire Observational Study Observational Study - 80 Unknown Restricted access Contact the principal investigator Access on specific project only