{"doc_desc":{"title":"Etude longitudinale sur des femmes atteintes de cancers pelviens\/\u00e9tude de la qualit\u00e9 de vie","idno":"FRESH-PEF8137-fr","producers":[{"name":"Rajeev RAMANAH","affiliation":"CHU BESANCON (CHU)"}]},"study_desc":{"title_statement":{"idno":"FRESH-PEF8137-fr","IDno":{"metadata_no":[{"agency":"PEF","code":"8137"},{"agency":"FReSH","code":"FRESH-PEF8137"}]},"title":"Etude longitudinale sur des femmes atteintes de cancers pelviens\/\u00e9tude de la qualit\u00e9 de vie","alternate_title":"GYNEQOL"},"study_authorization":{"agency":[{"name":"CNIL"}]},"authoring_entity":[{"name":"Charles;COUTANT","firstname":"Charles","lastname":"COUTANT","type":"investigator","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/00pjqzf38","role":"organisation id"},{"title":"SIREN","uri":"778204271","role":"organisation id"}],"email":"ccoutant@cgfl.fr","affiliationName":"CENTR GEORGES FRANCOIS LECLERC","PILabo":"Centre 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theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/7de64596-5b0d-4977-8f98-b982ff2ec17d"},{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/284ca20c-beb4-4abe-99fa-ef4513358bad"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D006176"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D009774"}]},{"topic":"Oncologie","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/5784b7f1-c7ce-49d9-9f38-aebcda0ff41d"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D008495"}]},{"topic":"Tumeurs malignes des organes g\u00e9nitaux f\u00e9minins","vocab":"cim-11","extLink":[{"uri":"http:\/\/id.who.int\/icd\/entity\/751805133","title":"CIM-11"}]},{"topic":"D\u00e9terminants comportementaux","vocab":"health determinant"},{"topic":"D\u00e9terminants biologiques : Pr\u00e9dispositions g\u00e9n\u00e9tiques","vocab":"health determinant"},{"topic":"D\u00e9terminants socio-d\u00e9mographiques et \u00e9conomiques","vocab":"health determinant"},{"topic":"D\u00e9terminants environnementaux : Autres","vocab":"health determinant"},{"topic":"D\u00e9terminants biologiques","vocab":"health determinant"},{"topic":"D\u00e9terminants environnementaux","vocab":"health determinant"}],"purpose":"\u2022 Objectif principal Etude des facteurs (cliniques, biologiques, sociod\u00e9mographiques, comportementaux) associ\u00e9s \u00e0 la qualit\u00e9 de vie (QdV), en situation r\u00e9elle, chez des patientes pr\u00e9sentant un cancer gyn\u00e9cologique, \u00e0 savoir cancer de l\u2019endom\u00e8tre, cancer du col de l\u2019ut\u00e9rus, cancer de la vulve et du vagin et cancer de l\u2019ovaire. \u2022 Objectifs secondaires D\u00e9crire les caract\u00e9ristiques des patientes \u00e0 l\u2019inclusion D\u00e9crire et comparer les donn\u00e9es de QdV des patientes de la cohorte aux donn\u00e9es europ\u00e9ennes et fran\u00e7aises Comparer la QdV de patientes op\u00e9r\u00e9es pour les cancers de l\u2019endom\u00e8tre et du col de l\u2019ut\u00e9rus selon diff\u00e9rentes approches chirurgicales : Laparotomie versus c\u0153lioscopie Chirurgie robot-assist\u00e9e versus laparoscopie conventionnelle \u00c9valuer la QdV au cours et \u00ab au long terme \u00bb chez les patientes atteintes d\u2019un cancer de l\u2019ovaire et en particulier celles b\u00e9n\u00e9ficiant d\u2019une chimioth\u00e9rapie intra-p\u00e9riton\u00e9ale perop\u00e9ratoire en adjuvant Evaluer l\u2019impact des th\u00e9rapies cibl\u00e9es sur la QdV des patientes atteintes de cancers du col et de l\u2019ovaire Analyse du temps jusqu\u2019\u00e0 d\u00e9t\u00e9rioration de la QdV dans le cancer de l\u2019ovaire et recherche des facteurs associ\u00e9s \u00e0 la d\u00e9t\u00e9rioration D\u00e9terminer si la QdV est diff\u00e9rente selon le type histologique des cancers de l\u2019endom\u00e8tre Comparer les QdV des patientes ayant re\u00e7u ou non une CT adjuvante apr\u00e8s une chirurgie et de la radioth\u00e9rapie dans le cancer de l\u2019endom\u00e8tre \u00c9valuer l\u2019importance de la prise en charge pr\u00e9coce des patientes en soins palliatifs dans QdV Validation du questionnaire de sexualit\u00e9 SAQ en langue fran\u00e7aise","abstract":"","coll_dates":[{"start":"2015-01-01"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"['Bourgogne Franche-Comt\u00e9']","analysis_unit":"Individus","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"value\": \"F\u00e9minin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D005260\"\n            }\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"value\": \"Adulte (19 \u00e0 24 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D055815\"\n            }\n        },\n        {\n            \"value\": \"Adulte (25 \u00e0 44 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000328\"\n            }\n        },\n        {\n            \"value\": \"Adulte (45 \u00e0 64 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008875\"\n            }\n        },\n        {\n            \"value\": \"Personne \u00e2g\u00e9e (65 \u00e0 79 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000368\"\n            }\n        },\n        {\n            \"value\": \"Grand \u00e2ge (80 ans et plus)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000369\"\n            }\n        }\n    ],\n    \"level_type_clusion_I\": \"Patients\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"Les cancers pelviens retenus seront les cancers du col de l\u2019ut\u00e9rus, du corps ut\u00e9rin, de l\u2019ovaire, du vagin  et de la vulve, quelque soit le type histologique et le stade : - Suivis en Franche-Comt\u00e9 et au Centre Georges Fran\u00e7ois Leclerc \u00e0 Dijon - \u00c2ge : 18 ans et plus - Ma\u00eetriser la langue fran\u00e7aise - \u00catre en mesure de r\u00e9pondre aux questionnaires (pas de troubles cognitifs majeurs) - R\u00e9sidant en Franche Comt\u00e9 ou en Bourgogne au moment du diagnostic - Avoir sign\u00e9 le consentement - Etre affili\u00e9e \u00e0 la S\u00e9curit\u00e9 Sociale\",\n    \"clusion_E\": \"\"\n}","data_kind":"['Donn\u00e9es cliniques','Donn\u00e9es rapport\u00e9es par le participant de l'\u00e9tude','Donn\u00e9es biologiques','Donn\u00e9es 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