Multiple Morbidities for Elderly People with Breast Cancer FRESH-PEF8125-en Laure DE DECKER Multiple Morbidities for Elderly People with Breast Cancer PAMS FRESH-PEF8125-en 8125 FRESH-PEF8125 Laure DE DECKER CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES Epidemiology France Portal (PEF) null Laure;DE DECKER Comorbidity oncological therapeutic toxicities geriatrics Oncology Geriatrics Gynaecology and obstetrics Malignant neoplasms of breast Biological determinants: Genetic predisposition Behavioral determinants Healthcare system determinants: Use of care Biological determinants Healthcare system determinants The main objective of the PAM study is to develop a prognostic score at 5-year survival for patients older than 65 years who have breast cancer. This score is calculated from breast cancer variables, medical, psychological and social characteristics, burden of morbidity, frailty and quality of life. Secondary objectives of the PAMS study are: - To investigate the influence of individually analysed geriatric parameters on choice of oncology treatment at 3 months. - To investigate the influence of quality of life on survival and the onset of toxicity at 3 months, 1 year and 5 years. To investigate the change in quality of life for patients at 3 months (immediately post-treatment), at 1 year (during chronic treatment and follow-up) and at 5 years. - To study changes in perception (Response Shift) over time through quality of life questionnaires, so as to distinguish between what is a change in perception and what is a change in quality of life when analysing changes in quality of life scores - To study the links between changes in perception over time through quality of life questionnaires and scores from Impact of Cancer questionnaires (IOC). - To evaluate the change in physical performance and autonomy in patients at 3 months, 12 months and 5 years. - To investigate the validity of the Lee Survival Score in this population at 5 years. - To investigate the geriatric and oncological parameters associated with sought medical healthcare, defined by unscheduled hospitalisation in the year following enrolment, at 3 months, 1 year and 5 years. - To assess the association between self-administered health questionnaires and geriatric evaluation parameters for this population. - To determine associations between prognostic score, onset of toxicity and oncology therapy at 5 years. - To determine associations between geriatric parameters, onset of toxicity and oncology therapy at 5 years. - To determine the most efficient comorbidity scale for estimating the tolerance to treatment offered to elderly people with breast cancer by stratifying tumour type and initial grade, as well as choice of treatment at 1 year. null France Pays de la Loire Individuals Patients population Female Aged (65 to 79 years) Aged, 80 and over (80 years and more) Individuals over 65 years of age - Individuals diagnosed with breast cancer by anatomopathological confirmation - Individuals that have given written informed consent to participate in the study or informed consent by the person legally responsible. - Subjects covered by a social security scheme. - Subjects monitored by a cancer treatment centre or oncology service participating in the study. Clinical data Participant-reported health data Biological data Health event/morbidity Health event/mortality Health care consumption and services Quality of life/health perception Other Through organizations (health services or institutions schools businesses etc.) [500-1000[ individuals Converting or copying information into a structured record Observational Study Observational Study Cohort study 800 Unknown Restricted access Contact the principal investigator Access on specific project only