Therapeutic strategies including Avastin as 1st line therapy in elderly patients suffering from advanced (IIIB/IV Stage) non-squamous non-small cell lung cancer, in routine clinical practice FRESH-PEF74114-en Camille BACHOT Therapeutic strategies including Avastin as 1st line therapy in elderly patients suffering from advanced (IIIB/IV Stage) non-squamous non-small cell lung cancer, in routine clinical practice AVANTAGE FRESH-PEF74114-en 74114 FRESH-PEF74114 NCT01893268 F. HOFFMANN-LA ROCHE AG Epidemiology France Portal (PEF) null ;Medical data center Bevacizumab Oncology Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, haematopoietic, central nervous system or related tissues Healthcare system determinants: Use of care Healthcare system determinants In each cohort of patients defined by their age classification ([65; 70[ and >=70 years), outcome measures are as follows: - Antineoplastic agents combined with bevacizumab as 1st line therapy - Classes of antineoplastic agents combined with bevacizumab as 1st line therapy (platinum salt, taxanes,…) - Supportive care (growth factors, analgesics). to describe: - Characteristics of advanced nsNSCLC patients treated with bevacizumab as first-line therapy, and their disease characteristics, - Progression-Free Survival (PFS) and Overall Survival (OS), - Evolution of patients’ quality of life over the treatment period with bevacizumab as first-line therapy, - Safety of bevacizumab, - Reasons for non-use of bevacizumab as first-line therapy in patients suffering from advanced nsNSCLC. null France Individuals Patients population Male Female Aged (65 to 79 years) Aged, 80 and over (80 years and more) Inclusion criteria : - Patient aged >= 65 years, - Diagnosed with advanced nsNSCLC (stage IIIB or IV), - For whom the physician has decided to initiate a treatment with bevacizumab combined with chemotherapy as 1st line therapy, - Having received oral and written information about the study, and having signed a written consent form. Clinical data GCP/GVP Other Through organizations (health services or institutions schools businesses etc.) < 500 individuals Converting or copying information into a structured record Interview with the participant (including clinical) Observational Study Observational Study Cohort study 277 Unknown Restricted access Access on specific project only