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<docDscr>
  <citation>
    <titlStmt>
      <titl>NATIONAL REAL-LIFE STUDY OF LYMPHOMAS</titl>
      <IDNo>FRESH-PEF73987-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="LYSARC - THE LYMPHOMA ACADEMIC RESEARCH ORGANISATION" role="">Fanny CHERBLANC</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
</docDscr>
<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                NATIONAL REAL-LIFE STUDY OF LYMPHOMAS            </titl>
      <altTitl>
                    REALYSA                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF73987-en            </IDNo>
      <IDNo agency="PEF">
                    73987                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF73987                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Hervé GHESQUIERES                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="HOSPICES CIVILS DE LYON (HCL)">
        <ExtLink title="ROR" URI="https://ror.org/01502ca60" role="organisation id"/>
        <ExtLink title="SIREN" URI="266900273" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Fanny CHERBLANC                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="LYSARC - THE LYMPHOMA ACADEMIC RESEARCH ORGANISATION">
        <ExtLink title="ROR" URI="https://ror.org/0106jdf02" role="organisation id"/>
        <ExtLink title="SIREN" URI="432730919" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="Interlymph" type="collaboration">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            HOSPICES CIVILS DE LYON (HCL)                    
                                    </producer>
      <producer role="sponsor">
                                            LYSARC - THE LYMPHOMA ACADEMIC RESEARCH ORGANISATION                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="LYSARC - THE LYMPHOMA ACADEMIC RESEARCH ORGANISATION" email="fanny.cherblanc@lysarc.org">
                    Fanny;CHERBLANC
                                            <ExtLink title="ROR" URI="https://ror.org/0106jdf02" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="432730919" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-17"/>
      <distDate date="2026-06-17"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    Prognostic factors</keyword>
      <keyword vocab="" vocabURI="">
                    Therapeutic management</keyword>
      <keyword vocab="" vocabURI="">
                    Biobanks</keyword>
      <keyword vocab="" vocabURI="">
                    Prospective study</keyword>
      <keyword vocab="" vocabURI="">
                    Multicentric</keyword>
      <keyword vocab="" vocabURI="">
                    Environmental exposure</keyword>
      <keyword vocab="" vocabURI="">
                    Occupational exposure</keyword>
      <keyword vocab="" vocabURI="">
                    Care pathway</keyword>
      <keyword vocab="" vocabURI="">
                    Pesticides</keyword>
      <topcClas vocab="health theme">
                        Hematology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/9239f328-78c9-40a5-a0b9-8e66fd9b6245"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D006402"/>
                                                </topcClas>
      <topcClas vocab="cim-11">
                        Neoplasms of haematopoietic or lymphoid tissues                                            </topcClas>
      <topcClas vocab="health determinant">
                        Socio-demographic and economic determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants: Eating habits                    </topcClas>
      <topcClas vocab="health determinant">
                        Environmental determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants: Use of care                    </topcClas>
      <topcClas vocab="health determinant">
                        Socio-demographic and economic determinants: Employment                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">Set up a real-life epidemiological platform for lymphoma prognosis in France, including epidemiological, clinical and biological data, with prospective follow-up of patients for up to 9 years.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2018-01-01"/>
      <collDate event="end" date="2028-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">Patients population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055815"/>
                                                    </universe>
      <universe level="age" clusion="I">Adult (25 to 44 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000328"/>
                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008875"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged (65 to 79 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000368"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged, 80 and over (80 years and more)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000369"/>
                                                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Participant-reported health data</dataKind>
      <dataKind>Biological data</dataKind>
      <dataKind>Socio-demographic data</dataKind>
      <dataKind>Paraclinical data (non-biological) : Imaging</dataKind>
    </sumDscr>
    <qualityStatement>
      <standardsCompliance>
        <standard>
          <standardName>WHO 2016 diagnostic classification</standardName>
          <standardName>MEDDRA extract for adverse events</standardName>
        </standard>
      </standardsCompliance>
      <otherQualityStatement>Data validation within eCRF (queries)</otherQualityStatement>
      <otherQualityStatement>consistency test in SAS</otherQualityStatement>
      <otherQualityStatement>quality control by sampling with comparison to the source file</otherQualityStatement>
    </qualityStatement>
  </stdyInfo>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Through organizations (health services or institutions</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>schools</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>businesses</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>etc.)</unitType>
        </frameUnit>
      </sampleFrame>
      <collMode>Self-administered questionnaire                                                            <concept vocab="CESSDA" vocabURI="SelfAdministeredQuestionnaire"/>
                                                    </collMode>
      <collMode>Interview with the participant (including clinical)                                                            <concept vocab="CESSDA" vocabURI="Interview"/>
                                                    </collMode>
      <sources>
        <sources>
          <sourceCitation>
                                    
                                    
                                                                    </sourceCitation>
          <srcOrig>Medico-administrative database</srcOrig>
        </sources>
      </sources>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <notes subject="observational study method">
                        Cohort study                    </notes>
    <anlyInfo>
      <respRate>6000</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <conditions>All projects must be validated by the REALYSA Scientific Committee and approved by the LYSA Board, on the basis of a synopsis (available on request). The REALYSA Scientific Committee meets quarterly. A contract will be drawn up for each project.</conditions>
    </useStmt>
  </dataAccs>
</stdyDscr>
<dataDscr>
</dataDscr></codeBook>
