{"study_desc":{"title_statement":{"idno":"FRESH-PEF73973-en","IDno":{"metadata_no":[{"agency":"PEF","code":"73973"},{"agency":"FReSH","code":"FRESH-PEF73973"}]},"title":"Comparison of strategies based on RT-PCR or antigenic testing for screening for SARS-CoV-2 infection in the general population from self-samples.","alternate_title":"AutoCoV"},"study_authorization":{"agency":[{"name":"CNIL"}]},"authoring_entity":[{"name":"Julie;GAGNAIRE","firstname":"Julie","lastname":"GAGNAIRE","type":"investigator","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/04pn6vp43","role":"organisation id"},{"title":"SIREN","uri":"264200304","role":"organisation id"},{"uri":"162520751","role":"pi id","title":"IdRef"}],"email":"julie.gagnaire@chu-st-etienne.fr","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT-ETIENNE","PILabo":"CHU de Saint-Etienne","isContact":true},{"name":"Bruno;POZZETTO","firstname":"Bruno","lastname":"POZZETTO","type":"investigator","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/04pn6vp43","role":"organisation id"},{"title":"SIREN","uri":"264200304","role":"organisation id"},{"uri":"0000-0002-2603-8467","role":"pi id","title":"ORCID"},{"uri":"058490574","role":"pi id","title":"IdRef"}],"email":"bruno.pozzetto@chu-st-etienne.fr","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT-ETIENNE","PILabo":"CHU de Saint-Etienne","isContact":true}],"oth_id":[{"name":""}],"production_statement":{"prod_place":"Epidemiology France Portal (PEF)","producers":[{"name":"CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT-ETIENNE","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/04pn6vp43","role":"sponsor id"},{"title":"SIREN","uri":"264200304","role":"sponsor 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theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/fa2ceeab-3b2f-45e9-9243-e5a8005b98de"},{"title":"MeSH","uri":"D055552"}]},{"topic":"COVID-19","vocab":"cim-11","extLink":[{"uri":"http:\/\/id.who.int\/icd\/entity\/1730556128","title":"CIM-11"}]}],"purpose":"The main objective is to evaluate, for the screening of SARSCoV-2 infection, the performance of a strategy that would combine 1) a salivary self-sampling associated with a previous nasal self-sampling and 2) an antigenic diagnostic test that can be directly performed in the field, in comparison with the reference technique of RT-PCR on salivary samples recently validated by the HAS. ; Secondary objectives:; - Determine the prevalence of SARS-CoV-2 infection in the population tested by the reference test ;; - Determine the prevalence of circulation of the different SARS-CoV-2 variants of interest in the population tested ;; - Evaluate the acceptability of self-sampling as a function of age and socio-professional category;; - Evaluate the feasibility of the two screening strategies;; - Evaluate the cost-effectiveness of the new diagnostic strategy compared with the reference technique (RT-PCR on saliva);; - Reinforce adherence to barrier measures and instructions for early isolation of positive cases, by means of rapid tests and support from people trained in the motivational approach;; - Evaluate health support for people in isolation;; - Evaluate, on a sample of positive and negative test subjects, knowledge of barrier measures and isolation instructions, through the use of rapid tests and support from anti-COVID mediators.","abstract":"","coll_dates":[{"start":"2021-01-01","end":"2021-12-31"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"['Auvergne 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in saliva - Number and percent of variants of SARS-CoV-2 interest compared to total number of positive strains","isDataInBiobank":true,"biobankContent":[],"biobankContentOther":"","dataTypeOther":""},"variableDictionnary":{"variableDictionnaryAvailable":"","variableDictionnaryLink":""},"dataQuality":{"otherDocumentation":""},"mockSample":{"mockSampleAvailable":"","mockSampleLocation":""},"thirdPartySource":{"otherSourceType":[]},"isHealthTheme":true,"fileDscr":{"fileTxt":{"fileCitation":{"titlStmt":{"IDno":[]}}}}},"schematype":"survey"}