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<docDscr>
  <citation>
    <titlStmt>
      <titl>French Esogastric Cancers Database</titl>
      <IDNo>FRESH-PEF73435-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)" role="">Stéphanie DEVAUX</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
</docDscr>
<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                French Esogastric Cancers Database            </titl>
      <altTitl>
                    FREGAT                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF73435-en            </IDNo>
      <IDNo agency="PEF">
                    73435                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF73435                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Stéphanie DEVAUX                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)">
        <ExtLink title="ROR" URI="https://ror.org/02ppyfa04" role="organisation id"/>
        <ExtLink title="SIREN" URI="265906719" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Guillaume PIESSEN                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)">
        <ExtLink title="ROR" URI="https://ror.org/02ppyfa04" role="organisation id"/>
        <ExtLink title="SIREN" URI="265906719" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Florence RENAUD                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)">
        <ExtLink title="ROR" URI="https://ror.org/02ppyfa04" role="organisation id"/>
        <ExtLink title="SIREN" URI="265906719" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="38 French centers are participating to the clinico-biological database FREGAT - Networks of physicians, surgeons, pathologists, biologists and researchers" type="collaboration">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            INSTITUT NATIONAL DU CANCER (INCA)                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)" email="stephanie.devaux@chru-lille.fr">
                    Stéphanie;DEVAUX
                                            <ExtLink title="ROR" URI="https://ror.org/02ppyfa04" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="265906719" role="organisation id"/>
                                    </contact>
      <contact affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)" email="guillaume.piessen@chru-lille.fr">
                    Guillaume;PIESSEN
                                            <ExtLink title="ROR" URI="https://ror.org/02ppyfa04" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="265906719" role="organisation id"/>
                                    </contact>
      <contact affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE LILLE (CHU)" email="florence.renaud@chru-lille.fr">
                    Florence;RENAUD
                                            <ExtLink title="ROR" URI="https://ror.org/02ppyfa04" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="265906719" role="organisation id"/>
                                    </contact>
      <contact affiliation="INSTITUT REGIONAL DU CANCER DE MONTPELLIER (ICM)" email="antoine.adenis@icm.unicancer.fr">
                    Antoine;ADENIS
                                            <ExtLink title="ROR" URI="https://ror.org/02693j602" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="788214963" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-17"/>
      <distDate date="2026-06-17"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    humanities and social sciences</keyword>
      <keyword vocab="" vocabURI="">
                    clinical and biological database</keyword>
      <keyword vocab="" vocabURI="">
                    biomarkers</keyword>
      <keyword vocab="" vocabURI="">
                    therapeutic strategies</keyword>
      <keyword vocab="" vocabURI="">
                    therapeutic treatment</keyword>
      <keyword vocab="" vocabURI="">
                    quality of life</keyword>
      <topcClas vocab="health theme">
                        Oncology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/5784b7f1-c7ce-49d9-9f38-aebcda0ff41d"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D008495"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Gastroenterology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/a3898340-a42d-4f5e-a822-1de204a9a867"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D005762"/>
                                                </topcClas>
      <topcClas vocab="cim-11">
                        Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, haematopoietic, central nervous system or related tissues                                            </topcClas>
      <topcClas vocab="health determinant">
                        Socio-demographic and economic determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants: Genetic predisposition                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants: Use of care                    </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">To identify the clinical, biological and tumor variables associated with 3-year relapse in patients who are treated for stage I to IV esophageal or gastric cancer, through the establishment of a prospective, multicenter, clinico-biological database.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2014-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">Patients population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055815"/>
                                                    </universe>
      <universe level="age" clusion="I">Adult (25 to 44 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000328"/>
                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008875"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged (65 to 79 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000368"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged, 80 and over (80 years and more)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000369"/>
                                                    </universe>
      <universe clusion="I">Patients with carcinoma of the esophagus, esophagogastric junction or stomach, those who were newly diagnosed by biopsy, no matter the cancer subtype, tumor stage or envisaged treatment.  Man or woman ≥ 18 years of age.  Treatment-naive in relation to these particular cancers.  Covered by the social welfare scheme.  Patients who voluntarily signed an informed consent form for retrieval of blood samples, completion of questionnaires and collection of patient information                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Participant-reported health data</dataKind>
      <dataKind>Biological data</dataKind>
    </sumDscr>
    <qualityStatement>
      <standardsCompliance>
        <standard>
          <standardName>Ennov clinical Software</standardName>
        </standard>
      </standardsCompliance>
    </qualityStatement>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality
Quality of life/health perception</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Through organizations (health services or institutions</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>schools</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>businesses</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>etc.)</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>[10000-20000[ individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Interview with the participant (including clinical)                                                            <concept vocab="CESSDA" vocabURI="Interview"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <notes subject="observational study method">
                        Cohort study                    </notes>
    <anlyInfo>
      <respRate>15000</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <conditions>The form used to file a Scientific Research Project is available on the internet site (https://www.fregat-database.org/). The completed project will be sent to proofreaders from the scientific committee, and feedback will be sent to the investigator. The scientific relevance of the project will be evaluated, the type of resources required and their availability. Financial support for the project to pay for the outlet and centralization of data and samples will also be considered.</conditions>
    </useStmt>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
</stdyDscr>
<dataDscr>
</dataDscr></codeBook>
