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<docDscr>
  <citation>
    <titlStmt>
      <titl>Cross-sectional study of patients monitored in private practice, users of illegal active substances or medicines diverted from their therapeutic use or under substitution treatment for opioid dependence</titl>
      <IDNo>FRESH-PEF73301-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="UNIVERSITE D&amp;#x27;AIX MARSEILLE" role="">Xavier THIRION</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
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<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Cross-sectional study of patients monitored in private practice, users of illegal active substances or medicines diverted from their therapeutic use or under substitution treatment for opioid dependence            </titl>
      <altTitl>
                    OPEMA: Observation of drug dependence in outpatient medicine                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF73301-en            </IDNo>
      <IDNo agency="PEF">
                    73301                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF73301                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Elisabeth FRAUGER                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE (AP-HM)">
        <ExtLink title="ROR" URI="https://ror.org/002cp4060" role="organisation id"/>
        <ExtLink title="SIREN" URI="261300081" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Joëlle MICALLEF                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE (AP-HM)">
        <ExtLink title="ROR" URI="https://ror.org/002cp4060" role="organisation id"/>
        <ExtLink title="SIREN" URI="261300081" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Samira MILOUDI                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="UNIVERSITE D&amp;#039;AIX MARSEILLE">
        <ExtLink title="ROR" URI="https://ror.org/035xkbk20" role="organisation id"/>
        <ExtLink title="SIREN" URI="130015332" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Veronica ORLEANS                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="UNIVERSITE D&amp;#039;AIX MARSEILLE">
        <ExtLink title="ROR" URI="https://ror.org/035xkbk20" role="organisation id"/>
        <ExtLink title="SIREN" URI="130015332" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Xavier THIRION                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="UNIVERSITE D&amp;#039;AIX MARSEILLE">
        <ExtLink title="ROR" URI="https://ror.org/035xkbk20" role="organisation id"/>
        <ExtLink title="SIREN" URI="130015332" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="" type="">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            AGENCE NATIONALE DE SECURITE DU MEDICAMENT ET DES PRODUITS DE SANTE (ANSM)                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE (AP-HM)" email="elisabeth.frauger@ap-hm.fr">
                    Elisabeth;FRAUGER
                                            <ExtLink title="ROR" URI="https://ror.org/002cp4060" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="261300081" role="organisation id"/>
                                    </contact>
      <contact affiliation="ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE (AP-HM)" email="joelle.micallef@ap-hm.fr">
                    Joëlle;MICALLEF
                                            <ExtLink title="ROR" URI="https://ror.org/002cp4060" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="261300081" role="organisation id"/>
                                    </contact>
      <contact affiliation="UNIVERSITE D'AIX MARSEILLE" email="xavier.thirion@ap-hm.fr">
                    Xavier;THIRION
                                            <ExtLink title="ROR" URI="https://ror.org/035xkbk20" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="130015332" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-17"/>
      <distDate date="2026-06-17"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    pharmacoepidemiology / consumption of psychoactive substances / general practitioners</keyword>
      <topcClas vocab="health theme">
                        General medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/4b9f8efb-68dd-45a1-b04c-d23d457d6898"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D058006"/>
                                                </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants: Addiction                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants: Use of care                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">Its main objective is to collect information on sociodemographic characteristics, consumption of products and the health status of patients in monitored in private practice, users of illegal active substances or medicines diverted from their therapeutic use or under substitution treatment for opioid dependence.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2008-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">General population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055815"/>
                                                    </universe>
      <universe level="age" clusion="I">Adult (25 to 44 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000328"/>
                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008875"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged (65 to 79 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000368"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged, 80 and over (80 years and more)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000369"/>
                                                    </universe>
      <universe clusion="I">Voluntary patients and consultants at a general practitioner’s clinic recruited and led by the CEIP                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Socio-demographic data</dataKind>
    </sumDscr>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health care consumption and services</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <timeMeth>Repeated cross-sectional study</timeMeth>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Through independent healthcare practitioners</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>[1000-10000[ individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <anlyInfo>
      <respRate>418 (2008), 628 (2009), 1385 (2010), 1516 (2011)</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Metadata-only access                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <conditions>Contact the principal investigator</conditions>
    </useStmt>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access not yet planned</relMat>
  </othrStdyMat>
</stdyDscr>
<dataDscr>
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