{"doc_desc":{"title":"\u00c9tude transversale sur des patients hospitalis\u00e9s pour arthrose ou consultant pour un bilan de m\u00e9nopause : insuffisance en vitamine D","idno":"FRESH-PEF73207-fr","producers":[{"name":"Michel LAROCHE","affiliation":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)"}]},"study_desc":{"title_statement":{"idno":"FRESH-PEF73207-fr","IDno":{"metadata_no":[{"agency":"PEF","code":"73207"},{"agency":"FReSH","code":"FRESH-PEF73207"}]},"title":"\u00c9tude transversale sur des patients hospitalis\u00e9s pour arthrose ou consultant pour un bilan de m\u00e9nopause : insuffisance en vitamine D","alternate_title":""},"study_authorization":{"agency":[{"name":"CNIL"}]},"authoring_entity":[{"name":"Michel;LAROCHE","firstname":"Michel","lastname":"LAROCHE","type":"investigator","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/017h5q109","role":"organisation id"},{"title":"SIREN","uri":"263100125","role":"organisation id"}],"email":"laroche.m@chu-toulouse.fr","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","PILabo":"CHU de Toulouse","isContact":true}],"oth_id":[{"name":""}],"production_statement":{"prod_place":"Portail Epid\u00e9miologie France (PEF)","producers":[{"name":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/017h5q109","role":"sponsor id"},{"title":"SIREN","uri":"263100125","role":"sponsor id"}],"role":"sponsor"}],"funding_agencies":[{"name":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/017h5q109"},{"title":"SIREN","uri":"263100125"}]}]},"distribution_statement":{"contact":[{"name":"Michel;LAROCHE","lastname":"LAROCHE","firstname":"Michel","type":"contact","email":"laroche.m@chu-toulouse.fr","affiliationName":"CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (CHUT)","contactPointLabo":"","extlink":[{"uri":"https:\/\/ror.org\/017h5q109","role":"organisation id","title":"ROR"},{"uri":"263100125","role":"organisation id","title":"SIREN"}]}]},"study_info":{"keywords":[{"keyword":"hyperparathyro\u00efdie"},{"keyword":"Vitamine D"},{"keyword":"ensoleillement"},{"keyword":"questionnaire"},{"keyword":"m\u00e9nopause"},{"keyword":"arthrose"}],"topics":[{"topic":"Endocrinologie","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/d1dd1bac-5313-4ab3-837f-4acd3ec521a7"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D004704"}]},{"topic":"Gyn\u00e9cologie et obst\u00e9trique","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/7de64596-5b0d-4977-8f98-b982ff2ec17d"},{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/284ca20c-beb4-4abe-99fa-ef4513358bad"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D006176"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D009774"}]},{"topic":"Rhumatologie","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/bfb0bafd-7894-45ba-84fc-ddab5fd6c537"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D012219"}]},{"topic":"Hyperparathyro\u00efdie","vocab":"cim-11","extLink":[{"uri":"http:\/\/id.who.int\/icd\/entity\/9633776","title":"CIM-11"}]},{"topic":"D\u00e9terminants environnementaux : Climat","vocab":"health determinant"},{"topic":"Syst\u00e8mes de soins et acc\u00e8s aux soins","vocab":"health determinant"},{"topic":"D\u00e9terminants comportementaux","vocab":"health determinant"},{"topic":"D\u00e9terminants environnementaux","vocab":"health determinant"}],"purpose":"Les objectifs sont : \u2022pr\u00e9ciser si l\u2019\u00e9valuation par questionnaire de l\u2019ensoleillement pouvait d\u00e9pister le risque d\u2019une insuffisance en vitamine D, dispensant alors \u00e9ventuellement du dosage dans les cas les plus simples ; \u2022d\u00e9terminer si l\u2019insuffisance en vitamine D entra\u00eenait, dans cette population saine, une hyperparathyro\u00efdie secondaire ; \u2022 savoir si cette \u00e9ventuelle hyperparathyro\u00efdie engendrait ou non une hyperr\u00e9sorption osseuse.","abstract":"","coll_dates":[{"start":"2011-01-01","end":"2011-12-31"}],"nation":[{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}}],"geog_coverage":"['Occitanie']","analysis_unit":"Individus","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"value\": \"Masculin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008297\"\n            }\n        },\n        {\n            \"value\": \"F\u00e9minin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D005260\"\n            }\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"value\": \"Adulte (45 \u00e0 64 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008875\"\n            }\n        }\n    ],\n    \"level_type_clusion_I\": \"Patients\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"Crit\u00e8res d\u2019inclusion : malades hospitalis\u00e9s ou vus en consultation tout au long de l\u2019ann\u00e9e 2011, afin d\u2019obtenir un nombre homog\u00e8ne de sujets pour chaque mois, par 5 m\u00e9decins rhumatologues, endocrinologues et physiologistes ayant con\u00e7u cette \u00e9tude, dans des services de rhumatologie (CHU et CHG), pour affections rachidiennes (lombalgies, radiculalgies) ou arthrose p\u00e9riph\u00e9rique, dans un service d\u2019exploration fonctionnelle r\u00e9nale o\u00f9 cette exploration \u00e9tait normale pour le m\u00e9tabolisme phosphocalcique, et dans un service de prise en charge de la m\u00e9nopause.\",\n    \"clusion_E\": \"\"\n}","data_kind":"['Donn\u00e9es rapport\u00e9es par le participant de l'\u00e9tude','Donn\u00e9es biologiques']","quality_statement":{"standards":[{"name":"","committee":"","governance":""}],"other_quality_statement":""}},"study_development":{"development_activity":[{"activity_type":"primary evaluation","activity_description":"Ev\u00e9nements de sant\u00e9\/morbidit\u00e9"}]},"method":{"data_collection":{"time_method":"Etude transversale non r\u00e9p\u00e9t\u00e9e","frequency":"","sampling_procedure":"['{\"concept\":{\"vocabURI\":\"Other\",\"vocab\":\"CESSDA\"},\"value\":\"Autre\"}']","sample_frame":{"frame_unit":{"unit_type":"['Via les professionnels d'exercice lib\u00e9ral Via des structures (services ou \u00e9tablissements de sant\u00e9, \u00e9coles, entreprises\u2026)']"}},"coll_mode":["{\"concept\":{\"vocabURI\":\"Interview\",\"vocab\":\"CESSDA\"},\"value\":\"Entretien avec le participant (dont clinique)\"}"],"research_instrument":"Acc\u00e8s restreint sur projet sp\u00e9cifique","sources":[],"target_sample_size":"[500-1000[ individus","response_rate":"528"},"method_notes":"Etude observationnelle","study_class":"\u00c9tude compl\u00e9t\u00e9e","notes":[{"subject":"research type","values":["Etude observationnelle"]}]},"data_access":{"dataset_availability":{"access_place":"","complete":"","status":"{\"value\":\"Acc\u00e8s r\u00e9serv\u00e9\",\"extLink\":[{\"title\":\"COAR\",\"uri\":\"http:\/\/purl.org\/coar\/access_right\/c_16ec\"}]}"},"dataset_use":{"restrictions":"","conditions":"Contacter le responsable scientifique","conf_dec":[{"txt":""}],"spec_perm":[{"txt":"","required":""}],"contact":[{"name":""}],"deposit_req":"","cit_req":""},"notes":""}},"additional":{"IsImport":true,"versionLang":"fr","originLang":"fr","autoTranslation":false,"status":"imported","creationDate":"25-08-2015","lastUpdatedAuto":null,"lastUpdatedManual":"13-09-2017","isContributorPI":false,"contributorName":"","contributorAffiliation":"","addTeamMember":"","obtainedAuthorization":{"otherAuthorizingAgency":[""]},"relatedDocument":[{"type":"","title":"","link":"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25960439"}],"regulatoryRequirements":{"conformityDeclaration":""},"fundingAgent":{"fundingAgentType":["Public (France)"],"otherFundingAgentType":[""]},"sponsor":{"sponsorType":["Public (France)"],"otherSponsorType":[""]},"governance":{"committee":""},"collaborations":{"networkConsortium":""},"theme":{"complementaryInformation":"","RareDiseases":""},"activeFollowUp":{"isActiveFollowUp":false,"followUpModeOther":""},"interventionalStudy":{"researchPurpose":[],"trialPhase":[],"interventionalStudyModel":"","isClinicalTrial":"","otherResearchPurpose":""},"isInclusionGroups":"","allocation":{"allocationMode":"","allocationUnit":""},"masking":{"maskingType":"","blindedMaskingDetails":[]},"arms":[],"intervention":[],"inclusionGroups":[],"collectionProcess":{"collectionModeDetails":"Questionnaire rempli par le patient avec l\u2019aide d\u2019infirmi\u00e8res ou d\u2019\u00e9tudiants en m\u00e9decine","collectionModeOther":""},"dataCollection":{"inclusionStrategyOther":"","samplingModeOther":"","recruitmentSourceOther":"","otherDocumentation":""},"dataCollectionIntegration":{"isDataIntegration":false},"geographicalCoverage":{"geoDetail":"Toulouse"},"dataTypes":{"clinicalDataDetails":"","biologicalDataDetails":"Le matin, \u00e0 jeun : calc\u00e9mie, phosphor\u00e9mie, albumin\u00e9mie, cr\u00e9atinin\u00e9mie. Le d\u00e9bit de filtration glom\u00e9rulaire (DFG) a \u00e9t\u00e9 estim\u00e9 \u00e0 partir de la cr\u00e9atinin\u00e9mie en utilisant la formule MDRD. Les concentrations de 25OH vitamine D totale (forme D2 et D3) de CTX (appel\u00e9s aussi Crosslaps\u00ae) ainsi que de PTH intacte ont \u00e9t\u00e9 analys\u00e9es par des dosages s\u00e9riques utilisant une technique d\u2019immuno-chemiluminescence automatis\u00e9e sur les automates Liaison\u00ae (Diasorin) pour la 25OH vitamine D et Cobas\u00ae (Roche) pour les deux autres param\u00e8tres.","isDataInBiobank":false,"biobankContent":[],"biobankContentOther":"","dataTypeOther":""},"variableDictionnary":{"variableDictionnaryAvailable":"","variableDictionnaryLink":""},"dataQuality":{"otherDocumentation":""},"mockSample":{"mockSampleAvailable":"","mockSampleLocation":""},"thirdPartySource":{"otherSourceType":[]},"isHealthTheme":true,"fileDscr":{"fileTxt":{"fileCitation":{"titlStmt":{"IDno":[]}}}}},"schematype":"survey"}