Case-Control Study on the Relation Between Systemic Sclerosis and Occupational Exposure FRESH-PEF73181-en Isabelle MARIE Case-Control Study on the Relation Between Systemic Sclerosis and Occupational Exposure FRESH-PEF73181-en 73181 FRESH-PEF73181 Isabelle MARIE CENTRE HOSPITALIER UNIVERSITAIRE ROUEN Epidemiology France Portal (PEF) CENTRE HOSPITALIER UNIVERSITAIRE ROUEN MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES PFIZER (FRANCE) null Isabelle;MARIE crystalline silica keytones occupational exposure solvents scleroderma smoking tobacco Clinical immunology Systemic sclerosis Behavioral determinants Environmental determinants Socio-demographic and economic determinants: Employment Socio-demographic and economic determinants The aim of the study is to investigate the relation between systemic sclerosis and occupational exposure, and to define the risk of systemic sclerosis in male and female patients that is linked to occupational exposure. null France Normandie Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) Patients with systemic sclerosis (declared) consulting at one of 3 participating centres (Departments of Internal Medicine, Dermatology and Pneumology in Rouen, Elbeuf and Le Havre) between 2005 and 2008. Controls: Subjects with a chronic illness or an acute illness who do not have: a connective tissue disorder; systemic vasculitis and other systemic autoimmune disorders; neoplasia and chronic interstitial lung disease. Participant-reported health data Health event/morbidity Other Through organizations (health services or institutions schools businesses etc.) < 500 individuals Converting or copying information into a structured record Observational Study Observational Study Case-control study 100 cases/300 controls Completed study Restricted access Contact the principal investigator Access on specific project only