<_value> Assessment of the Impact of Exposure to Occupational and Environmental Chemicals During Pregnancy on Pregnancy Outcome and Child Development PELAGIE FRESH-PEF73143-en 73143 FRESH-PEF73143 Cécile CHEVRIER INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) Epidemiology France Portal (PEF) AGENCE NATIONALE DE LA RECHERCHE (ANR) AGENCE NATIONALE DE SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL (ANSES) ARS BRETAGNE FONDATION DE FRANCE MINISTERE DU TRAVAIL ET DES SOLIDARITES SANTE PUBLIQUE FRANCE null Cécile;CHEVRIER CNIL Solvents Persistent Organic Polluants Water Disinfection by-products Pregnancy outcomes child development. Main cohort topics: Health and environment. Pesticides Endocrinology Gynaecology and obstetrics Paediatrics Nephrology Environmental determinants: Climate Environmental determinants: Other Behavioral determinants Environmental determinants Socio-demographic and economic determinants: Employment Socio-demographic and economic determinants General objective: to assess the impact of early-life exposure to occupational and environmental chemicals on pregnancy outcome and child development, including exposure to solvents, pesticides, persistants pollutants and chlorinated derivatives in water. Secondary objectives: - to identify environmental sources and individual determinants (socio-demographic characteristics, lifestyle, genetic susceptibility) of exposure to pollutants measured by biomarkers - to investigate the respective roles of prenatal exposure and exposure during childhood null France Bretagne Individuals General population Male Female Infant, Newborn (birth to 28 days) Child, Preschool (2 to 5 years) Child (6 to 12 years) Adolescent (13 to 18 years) Young Adult (19 to 24 years) Women in their first trimester of pregnancy (less than 19 weeks amenorrhoea) living in one of the "départements" participating in the study. Clinical data Biological data Participant-reported health data Health event/morbidity Health event/mortality Other Through organizations (health services or institutions schools businesses etc.) [1000-10000[ individuals Self-administered questionnaire Observational Study Observational Study Cohort study 3421 Unknown Restricted access Data may be used by academic teams To be decided if data may be used by industrial teams. Access on specific project only