Genetics nephropathy and sib pair study FRESH-PEF7206-en Michel MARRE Genetics nephropathy and sib pair study GENESIS FRESH-PEF7206-en 7206 FRESH-PEF7206 Michel MARRE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) Epidemiology France Portal (PEF) GROUPT ETUDE MALADIES METABOLIQUES SYST. (GEMMS) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES null Renal insufficiency myocardial infarction diabetes Endocrinology Nephrology Biological determinants: Genetic predisposition Biological determinants GENESIS study, aiming to complete the GENEDIAB study (genetics, nephropathy, diabetes) and the angevan mono-centric cohort Surgene, recruited in a transversal way type 1 diabetic patients presenting a diabetic nephropathy or protected against diabetic nephropathy and proposed them to include their related. The objective of the cohort has been to follow longitudinally the cardiovascular and renal future of type 1 diabetic patients, 4 to 8 years after their inclusion null Belgium France Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Type 1 diabetes+retinopathy at all stages+diabetic nephropathy or normo-albuminuria and normal kidney function. Clinical data Biological data Coherence request during after computer data entry. Follow-up data are considered with the last date as a closure date. Health event/morbidity Health event/mortality Other Through organizations (health services or institutions schools businesses etc.) [1000-10000[ individuals Interview with the participant (including clinical) Observational Study Observational Study Cohort study 1064 Unknown Restricted access To be defined iwth the scientific investigator Access on specific project only