Rhône Alpes birth defects registry FRESH-PEF69-en Emmanuelle AMAR Rhône Alpes birth defects registry REMERA FRESH-PEF69-en 69 FRESH-PEF69 Emmanuelle AMAR REGISTRE DES MALFORMATIONS EN RHONE ALPES (REMERA) Epidemiology France Portal (PEF) REGION AUVERGNE RHONE ALPES AGENCE NATIONALE DE RECHERCHES SUR LE SIDA ET LES HEPATITES VIRALES (ANRS MIE) AGENCE NATIONALE DE SECURITE DU MEDICAMENT ET DES PRODUITS DE SANTE (ANSM) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) null Emmanuelle;AMAR prevalence of congenital malformations reprotoxic risk factors antenatal screening eugenic abortions perinatality database on malformations epidemiology follow-up alert teratogens genetics Gynaecology and obstetrics Paediatrics Anencephaly or similar anomalies Structural developmental anomalies of eyelid, lacrimal apparatus or orbit Structural developmental anomaly of heart or great vessels Structural developmental anomalies of the nose or cavum Developmental anomalies Behavioral determinants: Addiction Socio-demographic and economic determinants Biological determinants: Genetic predisposition Healthcare system determinants: Use of care Environmental determinants: Other Behavioral determinants Behavioral determinants: Eating habits Environmental determinants Socio-demographic and economic determinants: Employment Biological determinants Healthcare system determinants Objectives in terms of public health: 1) Evaluation of the importance of the change in malformations (incidence, factors, appearance of a new malformation or of a new malformation symptom, space-time variations of these incidences) 2) Evaluation of the actions in public health: measure the impact of the actions implemented, especially perinatal screening and also the primary prevention initiatives on the prevalence of malformations and propose orientations for the development of health programs. 3) Alert in the case where a link with a teratogen, whether or not known, is suspected In terms of research: 1) Highlight the factors of risk of malformation 2) Study their interactions with susceptibilities of a genetic nature null France Auvergne Rhône-Alpes Individuals People with disabilities Male Female Other Infant, Newborn (birth to 28 days) Infant (28 days to 2 years) The following are included in the registry: Congenital malformations diagnosed antenatally or postnatally until the end of the first year of life. Clinical data Participant-reported health data Biological data Socio-demographic data Paraclinical data (non-biological) : Anthropometry Health event/morbidity Health event/mortality Other >= 20000 individuals Converting or copying information into a structured record Observational Study Observational Study Morbidity registry 61 000 (in 2012) Unknown Restricted access Data depersonalized Access to the data (depersonalized) is possible, on request Free access