Case-Control Study on Childhood Cancers FRESH-PEF6435-en Jacqueline CLAVEL Case-Control Study on Childhood Cancers ESCALE FRESH-PEF6435-en 6435 FRESH-PEF6435 Jacqueline CLAVEL INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) Epidemiology France Portal (PEF) null Jacqueline;CLAVEL Exposure hydrocarbon petrol benzine risk factors pollution child Oncology Hematology Clinical immunology Paediatrics Neoplasms Behavioral determinants: Addiction Biological determinants: Genetic predisposition Environmental determinants: Other Behavioral determinants Environmental determinants Biological determinants To investigate the influence of the following on childhood cancer risk: pregnancy outcome, child's characteristics at birth, child's environment in utero or during childhood, parents' profession and lifestyle, successive domicile communities, family history of cancer, birth defects, or autoimmune diseases. To identify genetic predispositions capable of modulating the function of these factors, including polymorphisms in genes involved in the transport and metabolism of xenobiotics, DNA repair, immune response, or in embryonic development and cell differentiation. To investigate the interactions between these polymorphisms and environmental factors. null France Individuals Patients population Male Female Infant, Newborn (birth to 28 days) Infant (28 days to 2 years) Child, Preschool (2 to 5 years) Child (6 to 12 years) Men or women - under 15 years old Clinical data Participant-reported health data Biological data Health event/morbidity Health event/mortality Other Through organizations (health services or institutions schools businesses etc.) [1000-10000[ individuals Converting or copying information into a structured record Interview with the participant (including clinical) Observational Study Observational Study Case-control study 3147: - 1466 cas/cases - 1681 témoins/controls Completed study Restricted access Access on specific project only