Registry of Congenital Malformations in Alsace (Certified Regisrtry) FRESH-PEF62-en Danaluiza TIMBOLSCHI Registry of Congenital Malformations in Alsace (Certified Regisrtry) REMACA FRESH-PEF62-en 62 FRESH-PEF62 Danaluiza TIMBOLSCHI UNIVERSITE DE STRASBOURG Epidemiology France Portal (PEF) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) SANTE PUBLIQUE FRANCE null Danaluiza;TIMBOLSCHI prenatal diagnosis Behavioral determinants: Addiction Socio-demographic and economic determinants Biological determinants: Genetic predisposition Healthcare system determinants: Use of care Socio-demographic and economic determinants: Employment Behavioral determinants Biological determinants Healthcare system determinants From an epidemiological standpoint: 1) Determination of frequency (in terms of prevalence) and distribution of congenital malformation; 2) Identification of the risk factors of malformations (discomfort, environment, medications and toxic) 3) Determination of malformation ""clusters"" for decision aids in the event of a significant increase in the prevalence of a malformation type (monitoring-alert); 4) Making data available for epidemiological studies From a public health standpoint 1) Assessment of the impact of health policies in the field of perinatal medicine and the impact of regional obstetric practices; 2) Measuring the effectiveness of the prevention and establishment of support to inform healthcare professionals, especially in the field of teratology; 3) Assessment of healthcare requirements in perinatal medicine (birthing methods and locations); From a clinical standpoint: 1) Locating new malformation associations and even the identification of new symptoms; 2) Determination of modes of genetic disorder transmission; 3) Establishment of interactions among various active partners in prevention, socio-educational care in the region concerned. null France Grand Est Individuals People with disabilities Male Female Infant, Newborn (birth to 28 days) Infant (28 days to 2 years) Reported cases of malformations visible at the clinical and visceral examination, as well as identified or non-identified malformation syndromes, including those linked to chromosomal defects until two years old.. Recorded cases in the both Alsace départements and where parents are only residing both Alsace départements. Clinical data Biological data Socio-demographic data Paraclinical data (non-biological) : Imaging CIM10 for malformations and diseases ATC code for medication. Health event/morbidity Health event/mortality Health care consumption and services Other [10000-20000[ individuals Other Observational Study Observational Study Morbidity registry About 700 cases per year since 2005. About 450 cases per year since 2005. Unknown Restricted access Individual data: on request. Free access