Cohort of patients overexposed during a course of conformal radiotherapy for a prostate adenocarcinoma in Jean Monnet Hospital in Epinal FRESH-PEF60188-en Jean-Marc SIMON Cohort of patients overexposed during a course of conformal radiotherapy for a prostate adenocarcinoma in Jean Monnet Hospital in Epinal EPOPA FRESH-PEF60188-en 60188 FRESH-PEF60188 Jean-Marc SIMON Tabassome SIMON Patrick GOURMELON ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP) Epidemiology France Portal (PEF) MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES null Jean-Marc;SIMON Tabassome;SIMON Patrick;GOURMELON doses irradiated tissues overexposure complications iatrogenic effects dosimetry Oncology Healthcare system determinants: Use of care Socio-demographic and economic determinants: Employment Healthcare system determinants Socio-demographic and economic determinants To correlate received doses and volume of irradiated normal tissues in the cohort of patients who underwent overexposure of varying degrees, as well as complications observed with biologic, phenotypic and genetic data. The incidence and severity of iatrogenic effects and sequelae of radiotherapy (according to soma-lent and CTCAE scales) are correlated using a precise reconstruction of actual irradiation dosimetry received by each patient (total radiation dose prescribed and issued by daily controls) according to technical dossier data and system treatment planning. Secondary objective: to gather biological collections from blood samples (serum bank, DNA bank, lymphocytes) to correlate iatrogenic complications and radiation doses to normal tissues with biologic, phenotypic and genetic data. These collections will be used to: - identify factors associated with susceptibility to radiation-induced complications in normal tissues; - study radiation fibrosis biology; - study normal tissue radiosensitivity: rectal wall; - study the biological control dose-response relationship for prostate adenocarcinoma; - implement radiogenic fibrosis treatment protocols. null France Grand Est Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) Patients treated for a prostate adenocarcinoma in the radiation department of the Jean Monnet Hospital between 2000 and 2006. Clinical data Participant-reported health data Biological data Health event/morbidity Health event/mortality Health care consumption and services Other Through organizations (health services or institutions schools businesses etc.) < 500 individuals Interview with the participant (including clinical) Observational Study Observational Study Cohort study 120 sujets inclus avec recueil sanguin / 120 with blood sample selection409 patients concernés, dont 29 sont décédés / 409 concerned with 29 deaths Unknown Restricted access To be decided if data may be used by academic teams. Data may not be used by industrial teams. Access on specific project only