Cohort of 1,000 Households for H1N1 Pandemic Follow-Up FRESH-PEF60168-en Fabrice CARRAT Cohort of 1,000 Households for H1N1 Pandemic Follow-Up COPANFLU FRESH-PEF60168-en 60168 FRESH-PEF60168 Antoine FLAHAULT Fabrice CARRAT ECOLE DES HAUTES ETUDES EN SANTE PUBLIQUE (EHESP) Epidemiology France Portal (PEF) ECOLE DES HAUTES ETUDES EN SANTE PUBLIQUE (EHESP) INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD) null Antoine;FLAHAULT Fabrice;CARRAT influenza A (H1N1) infectious respiratory syndromes Health episodes infections complications infection Infectious disease medicine Behavioral determinants Environmental determinants: Other Socio-demographic and economic determinants Environmental determinants General objective: To identify individual epidemiological, environmental, immunological, social, genetic and virological risk determinants of infection by influenza A (H1N1) swine-like-(SWL) virus Secondary Objectives: - to describe the impact on public health in terms of morbidity, complications and health care resources for A (H1N1)-SWL infection; - to characterise the “natural” history of the infection and its variability, to determine how it is transmitted; - to study the individual and collective determinants of the variable clinical expressions of the infection; - to study behavioural changes induced by pandemic and assess the level of risk perception and its evolution over time; - to evaluate penetrance, application and effectiveness of control measures in place (treatment, vaccination, barriers); - to characterise the homeotypic and heterotypic immunity of participants, according to age – evaluate herd immunity and to study innate and acquired cellular immunity subsequent to infection by this virus; - To characterise viral diversity and evolutionary mechanisms of virus A (H1N1)-SWL; to study the onset of drug resistance - to build and test anticipation models in real time on the impact of pandemic on the population and to simulate different control scenarios. null Bolivia, Plurinational State of Lao People's Democratic Republic Mali Cameroon France Individuals General population Male Female Infant, Newborn (birth to 28 days) Infant (28 days to 2 years) Child, Preschool (2 to 5 years) Child (6 to 12 years) Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) Volunteer households in the metropolitan area whose members have all provided validated consent to participate in this cohort (Parental consent as well as children's is required, optional if they are over 7 years old and obligatory if they are over 13 years); covered by health insurance; can write and speak French and who have a land-line telephone. Participant-reported health data Biological data Health event/morbidity Health event/mortality Other Population database for statistical purposes [1000-10000[ individuals Self-administered questionnaire Interview with the participant (including clinical) Observational Study Observational Study Cohort study 1451 Unknown Restricted access According to IRESP Charter and INSERM/EHESP convention Access on specific project only