{"doc_desc":{"title":"European Community Respiratory Health Survey","idno":"FRESH-PEF60146-fr","producers":[{"name":"B\u00e9n\u00e9dicte LEYNAERT","affiliation":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)"}]},"study_desc":{"title_statement":{"idno":"FRESH-PEF60146-fr","IDno":{"metadata_no":[{"agency":"PEF","code":"60146"},{"agency":"FReSH","code":"FRESH-PEF60146"}]},"title":"European Community Respiratory Health Survey","alternate_title":"ECRHS"},"study_authorization":{"agency":[{"name":"CNIL"}]},"authoring_entity":[{"name":"B\u00e9n\u00e9dicte;LEYNAERT","firstname":"B\u00e9n\u00e9dicte","lastname":"LEYNAERT","type":"investigator","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/02vjkv261","role":"organisation id"},{"title":"SIREN","uri":"180036048","role":"organisation id"}],"email":"benedicte.leynaert@inserm.fr","affiliationName":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","PILabo":"INSERM \/ U 700","isContact":true}],"oth_id":[{"name":"Implication dans un r\u00e9seau de cohorte : Par ailleurs, le protocole standardis\u00e9 d\u2019ECRHS a \u00e9t\u00e9 adopt\u00e9 dans d\u2019autres grandes cohortes \u00e9pid\u00e9miologiques sur les maladies respiratoires chez l\u2019adulte, comme l\u2019\u00e9tude SAPALDIA, en suisse, GEIRD, en Italie, ou encore EGEA, en France. La standardisation du recueil des donn\u00e9es au sein de ce r\u00e9seau de cohortes, permettra d\u2019envisager la r\u00e9alisation d\u2019analyses communes, comme cela a d\u00e9j\u00e0 \u00e9t\u00e9 r\u00e9alis\u00e9, par exemple, sur les donn\u00e9es ECRHS+SAPALDIA. Inclusion dans un projet europ\u00e9en : ECRHS I et ECRHS II ont \u00e9t\u00e9 soutenues par 2 projets Europ\u00e9ens, dans les cadres des PCRD5 et PCRD6 de l'Union Europ\u00e9enne. L'\u00e9tude ECRHS fait de plus partie des projets europ\u00e9ens \u00ab GABRIEL \u00bb sur la g\u00e9n\u00e9tique de l'asthme (http:\/\/www.gabriel-fp6.org\/) et \u00ab ESCAPE \u00bb sur la polution atmosph\u00e9rique (http:\/\/www.escapeproject.eu).","type":"collaboration"}],"production_statement":{"prod_place":"Portail Epid\u00e9miologie France (PEF)","producers":[{"name":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/02vjkv261","role":"sponsor id"},{"title":"SIREN","uri":"180036048","role":"sponsor id"}],"role":"sponsor"}],"funding_agencies":[{"name":""}]},"distribution_statement":{"contact":[{"name":"B\u00e9n\u00e9dicte;LEYNAERT","lastname":"LEYNAERT","firstname":"B\u00e9n\u00e9dicte","type":"contact","email":"benedicte.leynaert@inserm.fr","affiliationName":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","contactPointLabo":"","extlink":[{"uri":"https:\/\/ror.org\/02vjkv261","role":"organisation id","title":"ROR"},{"uri":"180036048","role":"organisation id","title":"SIREN"}]}]},"study_info":{"keywords":[{"keyword":"fonction pulmonaire"},{"keyword":"test allergologiques"},{"keyword":"monoxyde d'azote (NO) exhal\u00e9"},{"keyword":"\u00e9v\u00e9nements de sant\u00e9"},{"keyword":"environnement"}],"topics":[{"topic":"Allergologie","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/af65e2bf-afc5-45e8-a0fc-364dfb48f0a4"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D000486"}]},{"topic":"Immunologie m\u00e9dicale","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/7a3cf568-46ba-4840-be8f-f22fc030139f"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D000486"}]},{"topic":"Pneumologie","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/f6e18c52-6087-4662-904c-5c4b8174e40e"},{"title":"MeSH","uri":"http:\/\/id.nlm.nih.gov\/mesh\/D015272"}]},{"topic":"D\u00e9terminants environnementaux : Climat","vocab":"health determinant"},{"topic":"D\u00e9terminants environnementaux","vocab":"health determinant"},{"topic":"D\u00e9terminants environnementaux : Autres","vocab":"health determinant"}],"purpose":"Objectif g\u00e9n\u00e9ral : \u00c9tudier chez l'adulte en population g\u00e9n\u00e9rale, l'\u00e9volution de la fonction pulmonaire, et la survenue et l'\u00e9volution avec l'\u00e2ge, de l'asthme allergique et non allergique, et de la broncho-pneumopathie chronique obstructive (BPCO). Objectifs secondaires : - \u00c9tudier la survenue et l\u2019\u00e9volution avec l\u2019\u00e2ge des allergies respiratoires et de la BPCO chez des hommes et des femmes issus de la population g\u00e9n\u00e9rale et rechercher les associations avec des facteurs environnementaux et li\u00e9s au mode de vie en prenant en compte les interactions entre ces facteurs et d\u2019autres d\u00e9terminants personnels et biologiques. - Rechercher les associations entre la sensibilisation aux allerg\u00e8nes (atopie), les allergies respiratoires et le d\u00e9clin acc\u00e9l\u00e9r\u00e9 de la fonction pulmonaire et le d\u00e9veloppement de la BPCO. - \u00c9tudier l\u2019histoire naturelle (incidence, r\u00e9mission, s\u00e9v\u00e9rit\u00e9) de l\u2019asthme allergique et non allergique selon l\u2019\u00e2ge et le sexe. - \u00c9valuer les effets de l\u2019ob\u00e9sit\u00e9 et l\u2019int\u00e9r\u00eat de la perte de poids et de l\u2019activit\u00e9 physique sur la s\u00e9v\u00e9rit\u00e9 de l\u2019asthme et le d\u00e9clin de la fonction pulmonaire, et rechercher le r\u00f4le des hormones sexuelles et des hormones li\u00e9es \u00e0 l\u2019ob\u00e9sit\u00e9 telles que la leptine.","abstract":"","coll_dates":[{"start":"1990-01-01","end":"2001-01-01"}],"nation":[{"name":"Royaume-Uni","abbreviation":"gb","extLink":{"vocab":"ISO","vocabURI":"gb"}},{"name":"Su\u00e8de","abbreviation":"se","extLink":{"vocab":"ISO","vocabURI":"se"}},{"name":"Norv\u00e8ge","abbreviation":"no","extLink":{"vocab":"ISO","vocabURI":"no"}},{"name":"Allemagne","abbreviation":"de","extLink":{"vocab":"ISO","vocabURI":"de"}},{"name":"Italie","abbreviation":"it","extLink":{"vocab":"ISO","vocabURI":"it"}},{"name":"Espagne","abbreviation":"es","extLink":{"vocab":"ISO","vocabURI":"es"}},{"name":"France","abbreviation":"fr","extLink":{"vocab":"ISO","vocabURI":"fr"}},{"name":"Belgique","abbreviation":"be","extLink":{"vocab":"ISO","vocabURI":"be"}},{"name":"Congo","abbreviation":"cg","extLink":{"vocab":"ISO","vocabURI":"cg"}},{"name":"Islande","abbreviation":"is","extLink":{"vocab":"ISO","vocabURI":"is"}},{"name":"Danemark","abbreviation":"dk","extLink":{"vocab":"ISO","vocabURI":"dk"}}],"geog_coverage":"","analysis_unit":"Individus","universe":"{\n    \"level_sex_clusion_I\": [\n        {\n            \"value\": \"Masculin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D008297\"\n            }\n        },\n        {\n            \"value\": \"F\u00e9minin\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D005260\"\n            }\n        }\n    ],\n    \"level_age_clusion_I\": [\n        {\n            \"value\": \"Adulte (19 \u00e0 24 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D055815\"\n            }\n        },\n        {\n            \"value\": \"Adulte (25 \u00e0 44 ans)\",\n            \"concept\": {\n                \"vocab\": \"MeSH\",\n                \"vocabURI\": \"http:\\\/\\\/id.nlm.nih.gov\\\/mesh\\\/D000328\"\n            }\n        }\n    ],\n    \"level_type_clusion_I\": \"Population g\u00e9n\u00e9rale\",\n    \"level_type_clusion_other\": \"\",\n    \"clusion_I\": \"Hommes et femmes de la population g\u00e9n\u00e9rale \u00e2g\u00e9s de 20 \u00e0 44 ans en 1990-92\",\n    \"clusion_E\": \"\"\n}","data_kind":"['Donn\u00e9es cliniques','Donn\u00e9es rapport\u00e9es par le participant de l'\u00e9tude','Donn\u00e9es biologiques']","quality_statement":{"standards":[{"name":"","committee":"","governance":""}],"other_quality_statement":"['Pr\u00e9sence d\\'une requ\u00eate de coh\u00e9rence apr\u00e8s la saisie des donn\u00e9es informatiques Gestion des donn\u00e9es manquantes par retour au dossier source Relance des sujets pour r\u00e9aliser les visites de suivi Les patients sont inform\u00e9s de l\\'utilisation de leur donn\u00e9es']"}},"study_development":{"development_activity":[{"activity_type":"primary evaluation","activity_description":"Ev\u00e9nements de sant\u00e9\/morbidit\u00e9\r\nEv\u00e9nements de sant\u00e9\/mortalit\u00e9"}]},"method":{"data_collection":{"time_method":"","frequency":"","sampling_procedure":"['{\"concept\":{\"vocabURI\":\"Other\",\"vocab\":\"CESSDA\"},\"value\":\"Autre\"}']","sample_frame":{"frame_unit":{"unit_type":"['Via des structures (services ou \u00e9tablissements de sant\u00e9, \u00e9coles, entreprises\u2026)']"}},"coll_mode":["{\"concept\":{\"vocabURI\":\"SelfAdministeredQuestionnaire\",\"vocab\":\"CESSDA\"},\"value\":\"Questionnaire auto-administr\u00e9\"}","{\"concept\":{\"vocabURI\":\"Interview\",\"vocab\":\"CESSDA\"},\"value\":\"Entretien avec le participant (dont clinique)\"}"],"research_instrument":"Acc\u00e8s restreint sur projet sp\u00e9cifique","sources":[],"target_sample_size":"[1000-10000[ individus","response_rate":"1173"},"method_notes":"Etude observationnelle","study_class":"Inconnu","notes":[{"subject":"research type","values":["Etude observationnelle"]},{"subject":"observational study 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Utilisation possible des donn\u00e9es par des industriels \u00e0 d\u00e9terminer","conditions":"","conf_dec":[{"txt":""}],"spec_perm":[{"txt":"","required":""}],"contact":[{"name":""}],"deposit_req":"","cit_req":""},"notes":""}},"additional":{"IsImport":true,"versionLang":"fr","originLang":"fr","autoTranslation":false,"status":"imported","creationDate":"08-03-2013","lastUpdatedAuto":null,"lastUpdatedManual":"05-09-2017","isContributorPI":false,"contributorName":"B\u00e9n\u00e9dicte LEYNAERT","contributorAffiliation":"INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)","addTeamMember":"","obtainedAuthorization":{"otherAuthorizingAgency":[""]},"relatedDocument":[{"type":"","title":"List of publications in HAL","link":"http:\/\/www.hal.inserm.fr\/ECRHS"}],"regulatoryRequirements":{"conformityDeclaration":""},"fundingAgent":{"fundingAgentType":[],"otherFundingAgentType":[]},"sponsor":{"sponsorType":["Public (France)"],"otherSponsorType":[""]},"governance":{"committee":""},"collaborations":{"networkConsortium":true},"theme":{"complementaryInformation":"","RareDiseases":""},"activeFollowUp":{"isActiveFollowUp":true,"followUpModeOther":""},"interventionalStudy":{"researchPurpose":[],"trialPhase":[],"interventionalStudyModel":"","isClinicalTrial":"","otherResearchPurpose":""},"isInclusionGroups":"","allocation":{"allocationMode":"","allocationUnit":""},"masking":{"maskingType":"","blindedMaskingDetails":[]},"arms":[],"intervention":[],"inclusionGroups":[],"collectionProcess":{"collectionModeDetails":"Auto-questionnaire : saisie \u00e0 partir d\u2019un questionnaire papier (saisie manuelle) avec double saisie Entretiens : saisie \u00e0 partir d\u2019un questionnaire papier (saisie manuelle) avec double saisie Examens cliniques : \u00e9tape manuscrite (saisie manuelle) avec double saisie Examens biologiques : saisie directe","collectionModeOther":""},"dataCollection":{"inclusionStrategyOther":"","samplingModeOther":"","recruitmentSourceOther":"","otherDocumentation":""},"dataCollectionIntegration":{"isDataIntegration":false},"geographicalCoverage":{"geoDetail":"Cohorte multicentrique (24 centres) Internationale impliquant : UK, SWEDEN, NORWAY, GERMANY, ITALY, SPAIN, FRANCE, BELGIUM, SWITZERLAND, ISLAND, DANEMARK"},"dataTypes":{"clinicalDataDetails":"Examen clinique \u00e0 l\u2019inclusion et au cours du suivi tous les 9 ansInformations recueillies lors de l'examen clinique : fonction respiratoire, tests allergologiques, sang, s\u00e9rum","biologicalDataDetails":"Type de pr\u00e9l\u00e8vements r\u00e9alis\u00e9s : Sang, s\u00e9rum, (urine - \u00e9ventuellement lors du prochain suivi)","isDataInBiobank":true,"biobankContent":[],"biobankContentOther":"","dataTypeOther":""},"variableDictionnary":{"variableDictionnaryAvailable":"","variableDictionnaryLink":""},"dataQuality":{"otherDocumentation":""},"mockSample":{"mockSampleAvailable":"","mockSampleLocation":""},"thirdPartySource":{"otherSourceType":[]},"isHealthTheme":true,"fileDscr":{"fileTxt":{"fileCitation":{"titlStmt":{"IDno":[]}}}}},"schematype":"survey"}