<?xml version="1.0" encoding="UTF-8"?>
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<docDscr>
  <citation>
    <titlStmt>
      <titl>Longitudinal study in French Guiana: "Ecology of antibiotic resistance to Escherichia coli and Staphylococcus aureus in the commensal flora"</titl>
      <IDNo>FRESH-PEF60128-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="UNIVERSITE PARIS CITE" role="">Antoine ANDREMONT</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
</docDscr>
<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Longitudinal study in French Guiana: "Ecology of antibiotic resistance to Escherichia coli and Staphylococcus aureus in the commensal flora"            </titl>
      <altTitl>
                    ERAES                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF60128-en            </IDNo>
      <IDNo agency="PEF">
                    60128                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF60128                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Antoine ANDREMONT                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="UNIVERSITE PARIS CITE">
        <ExtLink title="ROR" URI="https://ror.org/05f82e368" role="organisation id"/>
        <ExtLink title="SIREN" URI="130025737" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="Involvement in cohort: neither the ERAES project nor a cohort that is part of a European network. All consortium members are French. However, a Dutch team (PR A. VAN BELKUM, UNIVERSITE ERASME) is involved with the project given its scientific competency in the blind analysis of DNA polymorphism in Amerindians included in the cohort. This association and its procedures were approved by the Bordeaux Ethical Research Committee." type="collaboration">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            AGENCE NATIONALE DE LA RECHERCHE (ANR)                    
                                    </fundAg>
      <fundAg>
                                            AGENCE NATIONALE DE SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL (ANSES)                    
                                    </fundAg>
      <fundAg>
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="UNIVERSITE PARIS CITE" email="antoine.andremont@gmail.com">
                    Antoine;ANDREMONT
                                            <ExtLink title="ROR" URI="https://ror.org/05f82e368" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="130025737" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-17"/>
      <distDate date="2026-06-17"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    effect</keyword>
      <keyword vocab="" vocabURI="">
                    antibiotics</keyword>
      <keyword vocab="" vocabURI="">
                    microorganisms</keyword>
      <keyword vocab="" vocabURI="">
                    target bacteria and yeast</keyword>
      <keyword vocab="" vocabURI="">
                    commensal flora</keyword>
      <keyword vocab="" vocabURI="">
                    ecology</keyword>
      <keyword vocab="" vocabURI="">
                    dissemination</keyword>
      <keyword vocab="" vocabURI="">
                    health events</keyword>
      <keyword vocab="" vocabURI="">
                    prescriptions</keyword>
      <keyword vocab="" vocabURI="">
                    progression</keyword>
      <keyword vocab="" vocabURI="">
                    environment</keyword>
      <topcClas vocab="health theme">
                        Infectious disease medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/fa2ceeab-3b2f-45e9-9243-e5a8005b98de"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D055552"/>
                                                </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants: Use of care                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">General objective: to monitor the changes in bacterial resistance and yeast colonisation in the commensal flora in a cohort of 157 Amerindians living in Trois-Sauts during rapid cultural transition. Secondary objective: to measure the changes in impact on bacterial resistance and yeast colonisation in the environment (animals, earth, water) during the same period.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2006-01-01"/>
      <collDate event="end" date="2012-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogCover>Guyane</geogCover>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">General population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055815"/>
                                                    </universe>
      <universe level="age" clusion="I">Adult (25 to 44 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000328"/>
                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008875"/>
                                                    </universe>
      <universe clusion="I">Adults living in Guiana                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Biological data</dataKind>
    </sumDscr>
    <qualityStatement>
      <otherQualityStatement>Request for consistency after data is processed electronically Missing data is managed by returning to source file or third party Subjects contacted again for follow-up visits Internal quality audits carried out during each campaign to obtain samples Patients are informed of the use of their data</otherQualityStatement>
    </qualityStatement>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Population database for statistical purposes</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>&lt; 500 individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Interview with the participant (including clinical)                                                            <concept vocab="CESSDA" vocabURI="Interview"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <anlyInfo>
      <respRate>165</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <restrctn>To be decided if data may be used by academic teams Data may not be used by industrial teams.</restrctn>
      <conditions>Access conditions for data use: possible for teams not belonging to a consortium only after project submission and approval by the cohort Scientific Council. Any possible additional analyses on stored samples shall be carried out after Ethical Research Committee approval obtained by the cohort Scientific Committee while preserving the anonymity of those involved.</conditions>
    </useStmt>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
</stdyDscr>
<dataDscr>
</dataDscr></codeBook>
