STANISLAS cohort FRESH-PEF60111-en Sophie VISVIKIS-SIEST STANISLAS cohort STANISLAS (Suivi Temporaire Annuel Non Invasif de la Santé des Lorrains Assurés Sociaux) FRESH-PEF60111-en 60111 FRESH-PEF60111 Sophie VISVIKIS-SIEST Maria STATHOPOULOU UNIVERSITE DE LORRAINE Epidemiology France Portal (PEF) null Sophie;VISVIKIS-SIEST Maria;STATHOPOULOU family determinants indicators cardiovascular risk cross-sectional longitudinal genetic environment Cardiology and vascular medicine General medicine Biological determinants: Genetic predisposition Biological determinants study the family determinants (genetic and environmental) of cardiovascular risk indicators and/or factors by using the model of the nuclear family. The 2 aspects, cross-sectional and longitudinal, are broached through specific designs. null France Grand Est Individuals General population Male Female Child (6 to 12 years) Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Nuclear families, at least 2 children/family, of French origin over 3 generations Clinical data Participant-reported health data Biological data Paraclinical data (non-biological) : Anthropometry Management of missing data: according to the missing information either exclusion of the subject or generation of variables Health event/morbidity Others Other Population database for statistical purposes [1000-10000[ individuals Self-administered questionnaire Interview with the participant (including clinical) Observational Study Observational Study 4295 patients / bilan 1 (1006 familles/families)2952 patients / bilan 2 (756 familles/families)359 patients / bilan 3 (99 familles/families) Unknown Restricted access Possible use of data by academic teams Possible use of data by manufacturers Access on specific project only