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<docDscr>
  <citation>
    <titlStmt>
      <titl>French Cohort on Neonatal Cerebral Artery Infarction</titl>
      <IDNo>FRESH-PEF60090-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)" role="">Stéphane CHABRIER</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
</docDscr>
<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                French Cohort on Neonatal Cerebral Artery Infarction            </titl>
      <altTitl>
                    AVCNN                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF60090-en            </IDNo>
      <IDNo agency="PEF">
                    60090                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF60090                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Stéphane CHABRIER                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)">
        <ExtLink title="ROR" URI="https://ror.org/02vjkv261" role="organisation id"/>
        <ExtLink title="SIREN" URI="180036048" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="" type="collaboration">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT-ETIENNE                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            APF FRANCE HANDICAP (APF)                    
                                    </fundAg>
      <fundAg>
                                            CENTRE HOSPITALIER UNIVERSITAIRE DE SAINT-ETIENNE                    
                                    </fundAg>
      <fundAg>
                                            FONDATION GARCHES                    
                                    </fundAg>
      <fundAg>
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                    
                                    </fundAg>
      <fundAg>
                                            MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)" email="stephane.chabrier@chu-st-etienne.fr">
                    Stéphane;CHABRIER
                                            <ExtLink title="ROR" URI="https://ror.org/02vjkv261" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="180036048" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-17"/>
      <distDate date="2026-06-17"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    History</keyword>
      <keyword vocab="" vocabURI="">
                    miscarriage</keyword>
      <keyword vocab="" vocabURI="">
                    primiparity</keyword>
      <keyword vocab="" vocabURI="">
                    first gestation</keyword>
      <keyword vocab="" vocabURI="">
                    twin pregnancy</keyword>
      <keyword vocab="" vocabURI="">
                    premature rupture of membranes</keyword>
      <keyword vocab="" vocabURI="">
                    caesarean section</keyword>
      <keyword vocab="" vocabURI="">
                    foetal distress</keyword>
      <keyword vocab="" vocabURI="">
                    monitoring</keyword>
      <keyword vocab="" vocabURI="">
                    medical care</keyword>
      <keyword vocab="" vocabURI="">
                    reeducation and rehabilitation</keyword>
      <keyword vocab="" vocabURI="">
                    information</keyword>
      <topcClas vocab="health theme">
                        Physical and Rehabilitation Medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/38e57437-b2cc-4d26-a46e-c5b639c01e5f"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D010810"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Paediatrics                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/bf8aaaac-ddee-41cd-bb8a-c5a63de3fcbd"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D010372"/>
                                                </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants: Genetic predisposition                    </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">General objective: to determine the clinical and biological obstetric-neonatal profile for full-term newborns presenting symptomatic arterial ischaemic stroke. Secondary objectives: - to determine the mechanisms of infarction from obstetric history, laboratory tests and imaging. - To monitor motor, cognitive and epileptic outcomes in children as well as their autonomy and quality of life until primary school.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2003-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">Patients population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Infant, Newborn (birth to 28 days)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D007231"/>
                                                    </universe>
      <universe level="age" clusion="I">Child (6 to 12 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002648"/>
                                                    </universe>
      <universe clusion="I">All participating newborns hospitalised by neonatal and paediatric neurology services. Full-term newborns presenting perinatal arterial ischaemic stroke were included i.e.: - presenting neurological symptoms (convulsions, malaise, hypotonia, impaired vigilance, asymmetric tone or motor skills) in the first 28 days of life; - Brain imaging (by CT or MRI scan) showing appearance of ischaemic-like lesions in an arterial location; - parents or those with parental authority who gave their consent after explanation of the protocol aims and modalities by the local investigating party and who received an explanatory document.                    </universe>
      <universe clusion="E">premature births; - asymptomatic neonates i.e. systematic discovery of an immediate pre- or post-natal image abnormality or children presenting with aposteriori cerebral palsy; - children with diffuse hypoxic-ischaemic lesions i.e more than three affected arterial territories or venous infarction; - where clinical and biological follow-up is impossible; - parental refusal to be included in the study or refusal to sign molecular biology consent form.                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Participant-reported health data</dataKind>
      <dataKind>Biological data</dataKind>
      <dataKind>Paraclinical data (non-biological) : Imaging</dataKind>
    </sumDscr>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Quality of life/health perception</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Through organizations (health services or institutions</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>schools</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>businesses</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>etc.)</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>&lt; 500 individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Self-administered questionnaire                                                            <concept vocab="CESSDA" vocabURI="SelfAdministeredQuestionnaire"/>
                                                    </collMode>
      <collMode>Interview with the participant (including clinical)                                                            <concept vocab="CESSDA" vocabURI="Interview"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <anlyInfo>
      <respRate>100</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <restrctn>Data may be used by academic teams To be decided if data may be used by industrial teams.</restrctn>
    </useStmt>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
</stdyDscr>
<dataDscr>
</dataDscr></codeBook>
