Cohort of Children Monitored After First Episode of Acute Demyelination FRESH-PEF60060-en Yann MIKAELOFF Cohort of Children Monitored After First Episode of Acute Demyelination KIDSEP FRESH-PEF60060-en 60060 FRESH-PEF60060 Yann MIKAELOFF ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP) Epidemiology France Portal (PEF) FONDATION FRANCE SCLEROSE EN PLAQUES (FONDATION FRANCE SEP) null Yann;MIKAELOFF multivariate analysis Health episodes child epidemiology Clinical immunology Neurology Biological determinants: Genetic predisposition Biological determinants General objective: 1. To follow a national cohort of children from their first episode of acute demyelination and monitor them for over 10 years 2. To determine the clinical and radiological risk factors of recurrence (qualified by MS diagnosis) 3. To determine the progression towards disability and its risk factors 4. To participate in a genetic study regarding MS susceptibility 5. Pharmacovigilance (vaccines) null France Individuals Patients population Male Female Infant (28 days to 2 years) Child, Preschool (2 to 5 years) Child (6 to 12 years) Children who have experienced clinical symptoms of acute inflammatory demyelination (A1) between January 1990 and December 2003 before the age of 16. Clinical data Participant-reported health data Paraclinical data (non-biological) : Imaging Health event/morbidity Health event/mortality Other Through organizations (health services or institutions schools businesses etc.) < 500 individuals Converting or copying information into a structured record Interview with the participant (including clinical) Observational Study Observational Study Cohort study 493 Unknown Metadata-only access Access on specific project only