Knee and Hip Osteoarthritis Long Term Assessment Cohort FRESH-PEF60059-en Francis GUILLEMIN Knee and Hip Osteoarthritis Long Term Assessment Cohort KHOALA FRESH-PEF60059-en 60059 FRESH-PEF60059 Francis GUILLEMIN CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE NANCY Epidemiology France Portal (PEF) SOCIETE FRANÇAISE DE RHUMATOLOGIE CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE NANCY INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) SANTE PUBLIQUE FRANCE CNAM null Francis;GUILLEMIN Prosthesis quality of life healthcare usage Rheumatology Osteoarthritis General objective: To describe the natural history of symptomatic hip and knee osteoarthritis and to to identify predictive factors of its consequences in terms of pain, functional incapacity, quality of life and healthcare (medical care, use of healthcare resources and illness cost). Patients for this cohort study are identified during a national prevalence study. Secondary objectives: - to investigate predictive factors for quality of life, changes in quality of life and hip or knee replacement such as: socio-demographic parameters, clinical factors, comorbidities, perceived health parameters at baseline (quality of life, functional capacity), x-rays and biological markers; - to identify factors that influence healthcare usage, social impact and treatment for symptomatic hip and knee osteoarthritis; - to collect and store biological samples (serum bank and DNA bank), x-rays, clinical and perceived health data in order to form a platform for other research projects, such as physiopathological projects on cellular and molecular mechanisms of osteoarthritis and genetic projects. This cohort will benefit from the advantages of the descriptive prevalence study and will allow the recruitment of a general population based representative sample. null France Individuals Patients population Male Female Middle Aged (45 to 64 years) Aged (65 to 79 years) Men and women between 40 and 75 years of age - Symptomatic uni- or bilateral knee (tibio-femoral) and hip osteoarthritis with confirmed diagnosis that meets EULAR and ACR criteria, identified from prevalent cases in France during cohort formation Clinical data Participant-reported health data Biological data Paraclinical data (non-biological) : Imaging Health event/morbidity Health event/mortality Other Through organizations (health services or institutions schools businesses etc.) [500-1000[ individuals Self-administered questionnaire Interview with the participant (including clinical) Observational Study Observational Study Cohort study 878 Unknown Restricted access Data may be used by academic teams. Data may be use by industrial teams. Access conditions: https://cohortekhoala.blogspot.com/ Collaboration with external teams is planned. Access to the constructed database is permitted by a partnership charter, which has been developed and already exhibited, mainly to potential partners, during communication concerning the cohort at the French Rheumatology Congress in 2008. Access on specific project only