Cohort of HIV-Infected Patients Treated with Interleukin-2 (IL-2). Study of Tolerance and Long-Term Clinical and Biological Progression of Immunotherapy Treatment. FRESH-PEF60058-en Jean-Pierre ABOULKER Cohort of HIV-Infected Patients Treated with Interleukin-2 (IL-2). Study of Tolerance and Long-Term Clinical and Biological Progression of Immunotherapy Treatment. ANRS CO14 IL-2 FRESH-PEF60058-en 60058 FRESH-PEF60058 Yves LEVY Jean-Pierre ABOULKER Dominique COSTAGLIOLA AGENCE NATIONALE DE RECHERCHES SUR LE SIDA ET LES HEPATITES VIRALES (ANRS MIE) Epidemiology France Portal (PEF) AGENCE NATIONALE DE RECHERCHES SUR LE SIDA ET LES HEPATITES VIRALES (ANRS MIE) null Yves;LEVY Neoplasia autoimmune disease systemic specific clinical progression immunovirology cardiovascular events Clinical immunology Infectious disease medicine Healthcare system determinants: Use of care Healthcare system determinants General objective: to study the long-term clinical tolerance of IL-2 treatment administered to patients infected with HIV. In particular, to monitor the occurrence of non-Hodgkin's lymphoma, neoplasia, systematic or specific autoimmune diseases and cardiovascular events, including venous or arterial thrombosis. Secondary objective: to investigate clinical progression (occurrence of events related to HIV and AIDS classification) and biological progression (CD4 and CD8 immune response and viral load) of HIV infection. null France Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) HIV-infected individuals over 18 years of age that have received at least one course of IL-2 in the ANRS trial or authorisation for temporary use, who have given signed consent and are affiliated members or beneficiaries of a social security scheme. Clinical data Biological data Paraclinical data (non-biological) : Anthropometry Request for consistency after data is processed electronically Missing data is managed by returning to source file or third party Health event/morbidity Health event/mortality Other Medical-administrative database (patients health insurance/mutual insurance) Disease and death registry [500-1000[ individuals Converting or copying information into a structured record Observational Study Observational Study Cohort study 613 Number of required subjects : [500-1000] Unknown Restricted access Data may be used by academic teams. Data may be used by industrial teams. For academic teams: Access in accordance with agreement from sponsor and Scientific Council. For indistrial teams: Access in accordance with agreement from sponsor, their Board of Directors and the cohort Scientific Council under contract. Access on specific project only