Enteric Neuropathy FRESH-PEF5972-en Arnaud BOURREILLE Enteric Neuropathy NEUROPATHIE ENTERIQUE (ENTERIC NEUROPATHY) FRESH-PEF5972-en 5972 FRESH-PEF5972 Arnaud BOURREILLE CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES Epidemiology France Portal (PEF) CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES null Arnaud;BOURREILLE phenotypic data demographic data computerised data bank biotherapy steroid dependence rheumatic skin eye and vascular extra-digestive symptoms hospital stays immunosuppressants health events consultation diagnosis surgery liver Neurology Gastroenterology Mitochondrial myopathies Biological determinants: Genetic predisposition Biological determinants General objective: to develop and expand the cohort and enteric neuropathy biological collection for patients with IBD and Parkinson's disease (PD). Secondary objectives: - Transcriptomic study of neuronal and glial plasticity; - Study and classification of neuro-degenerative processes; - Correlation of neuronal damage with clinical parameters and outlook. null France Pays de la Loire Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Enrolment includes all adult patients with IBD and PD monitored by the CHU in Nantes. Patients will be enrolled at time of diagnosis. Patients will be enrolled after disease diagnosis if phenotypic data included in the database are available in the source file. Blood will be taken during sampling in order to monitor patient disease. Biopsy samples will be taken during endoscopic examinations for conventional disease monitoring. underage patients, absence of study participation consent, lost to follow-up, phenotypic data not available from source file, PD patients with no digestive disorder requiring an endoscopy. Clinical data Participant-reported health data Biological data Consistency request after electronic data is recorded. Missing data is managed by returning to source file. Physician reminder for follow-up visits. Subject reminder for follow-up visits. Annual internal quality audit of database with 10% file analysis. Patients are informed about the use of their data. Health event/morbidity Health event/mortality Health care consumption and services Other < 500 individuals Interview with the participant (including clinical) Observational Study Observational Study Cohort study 100 IBD patients and 30 PD patients were included in the biological collection. These patients are part of the historical cohort. Phenotypic data is entered in the electronic database. Unknown Restricted access Data may be used by academic teams. Data may be used by industrial teams. Access conditions for biological collection are part of the Biobanque Ouest Atlantique (BOA, Western Atlantic Biobank) pending GIS-IBiSA certification request. Data will be available to other institutional research teams under contract. Data will be available to other private research teams under contract with CHU. Access on specific project only