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<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Longitudinal General Population Study: Pulmonary Nodule Detection by Computed Tomography (CT) Scan            </titl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF5906-en            </IDNo>
      <IDNo agency="PEF">
                    5906                </IDNo>
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                    FRESH-PEF5906                </IDNo>
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                    Guy LAUNOY                                                                                                                                        <ExtLink title="ORCID" URI="0000-0002-7052-0242" role="pi id"/>
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                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                                            <ExtLink title="ROR" URI="https://ror.org/02vjkv261" role="sponsor id"/>
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                                            CENTRE HOSPITALIER UNIVERSITAIRE DE CAEN NORMANDIE (CHU)                                            <ExtLink title="ROR" URI="https://ror.org/027arzy69" role="sponsor id"/>
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                                            AGENCE NATIONALE DE SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL (ANSES)                                            <ExtLink title="ROR" URI="https://ror.org/0471kz689"/>
                                            <ExtLink title="SIREN" URI="130012024"/>
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                                            CAISSE NATIONALE DE L&amp;#039;ASSURANCE MALADIE (CNAM)                                            <ExtLink title="ROR" URI="https://ror.org/03am7sg53"/>
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      <contact affiliation="INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)" email="guy.launoy@unicaen.fr">
                    Guy;LAUNOY
                                            <ExtLink title="ROR" URI="https://ror.org/02vjkv261" role="organisation id"/>
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      <depDate date="2026-10-16"/>
      <distDate date="2026-10-16"/>
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    <biblCit format="">
            </biblCit>
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    <notes> </notes>
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  <studyAuthorization>
    <authorizingAgency>CNIL                </authorizingAgency>
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  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    pulmonary nodule</keyword>
      <keyword vocab="" vocabURI="">
                    computed tomography scan</keyword>
      <keyword vocab="" vocabURI="">
                    asbestos</keyword>
      <topcClas vocab="health theme">
                        Oncology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/5784b7f1-c7ce-49d9-9f38-aebcda0ff41d"/>
                                                            <ExtLink title="MeSH" URI="D008495"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Pulmonary medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/f6e18c52-6087-4662-904c-5c4b8174e40e"/>
                                                            <ExtLink title="MeSH" URI="D015272"/>
                                                </topcClas>
      <topcClas vocab="health determinant">
                        Environmental determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Environmental determinants: Other                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants: Addiction                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">To prove that the presence of pulmonary nodules (by scan) increases the risk of developing lung cancer. To prove that there is no relationship between exposure to asbestos and the risk of developing lung cancer.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2003-01-01"/>
      <collDate event="end" date="2009-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
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      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">General population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="D055815"/>
                                                    </universe>
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                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="D008875"/>
                                                    </universe>
      <universe clusion="I">Male or female; - Not-working or retired.                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Paraclinical data (non-biological)</dataKind>
      <dataKind>Paraclinical data (non-biological) : Imaging</dataKind>
      <dataKind>Participant-reported health data</dataKind>
    </sumDscr>
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  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality
Health care consumption and services</description>
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    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
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          <unitType>Population database for statistical purposes</unitType>
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      <targetSampleSize>
        <sampleSizeFormula>[1000-10000[ individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Converting or copying information into a structured record                                                            <concept vocab="CESSDA" vocabURI="Transcription"/>
                                                    </collMode>
      <collMode>Interview with the participant (including clinical)                                                            <concept vocab="CESSDA" vocabURI="Interview"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
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    <stdyClas>Unknown</stdyClas>
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      <avlStatus>
                            To be defined                                                    </avlStatus>
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    <relMat>Access on specific project only</relMat>
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