{"study_desc":{"title_statement":{"idno":"FRESH-PEF5835-en","IDno":{"metadata_no":[{"agency":"PEF","code":"5835"},{"agency":"FReSH","code":"FRESH-PEF5835"}]},"title":"National transcatheter aortic valve implant registry","alternate_title":"FRANCE 2"},"study_authorization":{"agency":[{"name":"CNIL"}]},"authoring_entity":[{"name":"Martine;GILARD","firstname":"Martine","lastname":"GILARD","type":"investigator","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/03evbwn87","role":"organisation id"},{"title":"SIREN","uri":"200023059","role":"organisation id"},{"uri":"0000-0002-2794-7953","role":"pi id","title":"ORCID"},{"uri":"115383557","role":"pi id","title":"IdRef"}],"email":"","affiliationName":"CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE BREST (CHRU)","PILabo":"Centre Hospitalier Universitaire de \/ D\u00e9partement de cardiologie","isContact":false}],"oth_id":[{"name":"Edwards Lifesciences et Medtronic","type":"collaboration"}],"production_statement":{"prod_place":"Epidemiology France Portal (PEF)","producers":[{"name":"CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE BREST (CHRU)","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/03evbwn87","role":"sponsor id"},{"title":"SIREN","uri":"200023059","role":"sponsor id"}],"role":"sponsor"}],"funding_agencies":[{"name":"LIFESCIENCES","extlink":[{"title":"SIREN","uri":"429487507"}]},{"name":"MEDTRONIC FRANCE","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/03eraeg88"},{"title":"SIREN","uri":"722008232"}]},{"name":"MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES","extlink":[{"title":"ROR","uri":"https:\/\/ror.org\/01wp0c315"},{"title":"SIREN","uri":"130016546"}]}]},"distribution_statement":{"contact":[{"name":"","type":"contact"}]},"study_info":{"keywords":[{"keyword":"Catheter"},{"keyword":"transarterial approach"},{"keyword":"transfemoral approach"},{"keyword":"subclavian approach"},{"keyword":"transapical approach"},{"keyword":"surgical aortic valve replacement"},{"keyword":"Edwards Sapien"},{"keyword":"CoreValve"}],"topics":[{"topic":"Cardiology and vascular medicine","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/4455c187-2f2f-4cd1-a4dd-449f59d73b39 | http:\/\/data.europa.eu\/8mn\/euroscivoc\/c42fc6ec-b216-4a24-9e9d-f5e781c175a0"},{"title":"MeSH","uri":"D002309"}]},{"topic":"Emergency medicine","vocab":"health theme","extLink":[{"title":"ESV","uri":"http:\/\/data.europa.eu\/8mn\/euroscivoc\/5e1591e2-d02b-436c-8216-6b8912eee467"},{"title":"MeSH","uri":"D004635"}]},{"topic":"Biological determinants: Genetic predisposition","vocab":"health determinant"},{"topic":"Healthcare system determinants: Use of care","vocab":"health determinant"},{"topic":"Behavioral determinants","vocab":"health determinant"},{"topic":"Behavioral determinants: Eating habits","vocab":"health determinant"},{"topic":"Socio-demographic and economic determinants","vocab":"health determinant"},{"topic":"Biological determinants","vocab":"health determinant"},{"topic":"Healthcare system determinants","vocab":"health determinant"}],"purpose":"To demonstrate the utility of transcatheter aortic valve implantation in inoperable or high-risk patients who have tight aortic stenosis. 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