PRogestogens, EStrogens and STrOke FRESH-PEF5554-en Pierre-Yves SCARABIN PRogestogens, EStrogens and STrOke PRESSTO FRESH-PEF5554-en 5554 FRESH-PEF5554 Marianne CANONICO Pierre-Yves SCARABIN INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) Epidemiology France Portal (PEF) GIS-INSTITUT POUR LA RECHERCHE EN SANTE PUBLIQUE (IRESP) null Marianne;CANONICO Hormone therapy for menopause oestrogen progestin Gynaecology and obstetrics Neurology Cardiology and vascular medicine Stroke not known if ischaemic or haemorrhagic Healthcare system determinants: Use of care Healthcare system determinants To evaluate the risk of cardiovascular disease (cerebrovascular accident, myocardial infarction and pulmonary embolism) in connection with hormone therapy for menopause while considering the administration route for oestrogen and types of progestin. null France Individuals General population Female Middle Aged (45 to 64 years) Women - between 50 and 70 years old - menopausal Clinical data Socio-demographic data Health event/morbidity Health event/mortality Health care consumption and services Other Through organizations (health services or institutions schools businesses etc.) >= 20000 individuals Converting or copying information into a structured record Interview with the participant (including clinical) Observational Study Observational Study Case-control study 100000 - 20000 cas / case - 80000 témoins / controls Completed study Restricted access Only those involved in the project have access to data and are under the responsibility of the coordinator. Anonymised data is transmitted as an encrypted file whose decryption key is generated by the coordinator. Access on specific project only