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<docDscr>
  <citation>
    <titlStmt>
      <titl>Longitudinal Study of a Children Population With Bilateral Severe Cerebral Palsy: Incidence and Evolution of Orthopaedic Complications and Pain Related With These Complications.</titl>
      <IDNo>FRESH-PEF5282-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="HOSPICES CIVILS DE LYON (HCL)" role="">Isabelle POIROT</producer>
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<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Longitudinal Study of a Children Population With Bilateral Severe Cerebral Palsy: Incidence and Evolution of Orthopaedic Complications and Pain Related With These Complications.            </titl>
      <altTitl>
                    Cohort CP                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF5282-en            </IDNo>
      <IDNo agency="PEF">
                    5282                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF5282                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Isabelle POIROT                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="HOSPICES CIVILS DE LYON (HCL)">
        <ExtLink title="ROR" URI="https://ror.org/01502ca60" role="organisation id"/>
        <ExtLink title="SIREN" URI="266900273" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="Investigator annual meeting during the SFERHE study days (Soci&#xE9;t&#xE9; Francophone d&amp;#039 Etude et de Recherche sur les Handicaps de l&amp;#039 Enfance)" type="collaboration">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            HOSPICES CIVILS DE LYON (HCL)                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES                    
                                    </fundAg>
      <fundAg>
                                            SOCIETE FRANCOPHONE D ETUDES ET DE RECHERCHES SUR LES HANDICAPS DE L ENFANCE (S.F.E.R.H.E)                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="HOSPICES CIVILS DE LYON (HCL)" email="isabelle.poirot@chu-lyon.fr">
                    Isabelle;POIROT
                                            <ExtLink title="ROR" URI="https://ror.org/01502ca60" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="266900273" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-17"/>
      <distDate date="2026-06-17"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    pain</keyword>
      <keyword vocab="" vocabURI="">
                    child</keyword>
      <keyword vocab="" vocabURI="">
                    cohort</keyword>
      <keyword vocab="" vocabURI="">
                    orthopaedic complications</keyword>
      <keyword vocab="" vocabURI="">
                    epidemiology</keyword>
      <keyword vocab="" vocabURI="">
                    cerebral palsy</keyword>
      <topcClas vocab="health theme">
                        Physical and Rehabilitation Medicine                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/38e57437-b2cc-4d26-a46e-c5b639c01e5f"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D010810"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Neurology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/c4793dfe-e80e-49dd-9fcc-a1a742de1b25"/>
                                                            <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/00a5c4f4-b7ee-41a4-bcdf-3a02e6be1660"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D009462"/>
                                                </topcClas>
      <topcClas vocab="cim-11">
                        Cerebral palsy                                            </topcClas>
      <topcClas vocab="health determinant">
                        Socio-demographic and economic determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">The primary objective is to establish the incidence of orthopaedic complications (scoliosis and hip joint) depending on patients' age. Secondary objectives are to describe the sequences over time of these complications and the related pain, to explore the impact of nutrition, surgery, asymmetric postures and environmental factors, and to describe the medical and rehabilitative follow-up of these patients.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2009-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">Patients population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Child, Preschool (2 to 5 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002675"/>
                                                    </universe>
      <universe level="age" clusion="I">Child (6 to 12 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002648"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055815"/>
                                                    </universe>
      <universe clusion="I">Children aged from 2 to 10 years at inclusion, - with bilateral cerebral palsy (Brain injury or cerebral abnormalities ocurred before 2 years of age), - Grade IV or V of the GMFCS. - nonprogressive disease                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Paraclinical data (non-biological) : Imaging</dataKind>
    </sumDscr>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Through organizations (health services or institutions</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>schools</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>businesses</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>etc.)</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>&lt; 500 individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Converting or copying information into a structured record                                                            <concept vocab="CESSDA" vocabURI="Transcription"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <notes subject="observational study method">
                        Cohort study                    </notes>
    <anlyInfo>
      <respRate>311 (07/02/2017)</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            To be defined                                                    </avlStatus>
    </setAvail>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
</stdyDscr>
<dataDscr>
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