Observatory of Patients with laminopathies and emerinopathies FRESH-PEF5054-en Gisèle BONNE Observatory of Patients with laminopathies and emerinopathies OPALE FRESH-PEF5054-en 5054 FRESH-PEF5054 Karim WAHBI Gisèle BONNE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP) ASSOCIATION INSTITUT DE MYOLOGIE (AIM) Epidemiology France Portal (PEF) ASSISTANCE PUBLIQUE HOPITAUX DE PARIS (AP-HP) ASSOCIATION INSTITUT DE MYOLOGIE (AIM) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) null Karim;WAHBI Rabah;BEN YAOU Gisèle;BONNE Natural history muscular cardiac orthopaedic and metabolic involvements joint contractures cardiomyopathies premature aging progeria respiratory myopathies lipodystrophies Cardiology and vascular medicine Endocrinology Neurology Paediatrics Primary disorders of muscles Metabolic disorders Cardiomyopathy Biological determinants: Genetic predisposition Biological determinants to precise the natural history of musculrr, cardiac, respiratory, orthopaedic and metabolic involovements of patients suffering from laminopathies and emerinopathies. to identify cardiovascular, neurologic and respiratory prognosis factors. to identify obstetrical and perioperative complications related to laminopathies and emerinopathies. to identify correlations between LMNA/EMD gene mutations and the observated phenotypes. to have a repository ready for inclusion of patients in future therapeutic trials. null France Individuals Patients population Male Female Infant, Newborn (birth to 28 days) Infant (28 days to 2 years) Child, Preschool (2 to 5 years) Child (6 to 12 years) Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) all patient carrying a LMNA or a EMD gene mutation, including the paediatric population, registered to Social Security Helathcare System. Clinical data Biological data Socio-demographic data Paraclinical data (non-biological) : Imaging Paraclinical data (non-biological) : Other Health event/morbidity Health event/mortality Other Through organizations (health services or institutions schools businesses etc.) [500-1000[ individuals Interview with the participant (including clinical) Observational Study Observational Study 320 Unknown Restricted access data access to investigators Access on specific project only