Aluminium in water conveyance and Alzheimers disease FRESH-PEF3594-en Valérie GARCIA Aluminium in water conveyance and Alzheimers disease ALMA+ FRESH-PEF3594-en 3594 FRESH-PEF3594 Virginie RONDEAU UNIVERSITE DE BORDEAUX Epidemiology France Portal (PEF) AGENCE NATIONALE DE SECURITE SANITAIRE DE L ALIMENTATION DE L ENVIRONNEMENT ET DU TRAVAIL (ANSES) DANONE null Virginie;RONDEAU water silica Aluminium risk factors Neurology Psychiatry Biological determinants: Genetic predisposition Socio-demographic and economic determinants Biological determinants Study the relation between minerals in drinking water and especially aluminium, and the development of Alzheimers disease in 75 or more years old subjects. Verify if high concentrations of aluminium (more than 50mg/l of water) can improve the risk of dementia. null France Nouvelle-Aquitaine Individuals General population Male Female Aged (65 to 79 years) Aged, 80 and over (80 years and more) 75 or more years old subjects, exposed to high concentrations of aluminium in drinking water (Al>50mcg/l), residents in 14 towns of Dordogne, different than the ones included in the PAQUID cohort. 75 or more years old subjects participating to the PAQUID cohort, residents in one of the non-exposed towns (Al<50mcg/l) in Dordogne. subjects recently arrived in town. Inclusion period: May 1999 - January 2001. Clinical data Participant-reported health data Biological data Coherence request after computer data entry. Missing data asked back to the original file and/or to the patient. Health event/morbidity Health event/mortality Other Population database for statistical purposes < 500 individuals Interview with the participant (including clinical) Observational Study Observational Study Cohort study 400 Unknown Restricted access Data utilization possible for academic teams and for industrials. Access on specific project only