Longitudinal study of variants of BRCA1 and BRCA2 genes FRESH-PEF33456-en Fabienne LESUEUR Longitudinal study of variants of BRCA1 and BRCA2 genes BRCA Share FRESH-PEF33456-en 33456 FRESH-PEF33456 Sandrine CAPUTO Dominique STOPPA-LYONNET Fabienne LESUEUR INSTITUT CURIE Epidemiology France Portal (PEF) INSERM TRANSFERT INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) QUEST DIAGNOSTICS LTD UniCancer Group null Sandrine;CAPUTO Fabienne;LESUEUR ovary clinical and biological database BRCA1 BRCA2 cancer breast mutation Oncology Malignant neoplasms of breast Malignant neoplasms of ovary Biological determinants: Genetic predisposition Biological determinants The purpose of BRCA Share™ is to accelerate research on BRCA gene mutations, particularly on the variants of unknown significance, in order to improve the ability to diagnose and identify individuals predisposed to developing breast or ovarian cancer. null France Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) Patients with BRCA1 and BRCA2 gene mutations presenting at a participating centre Clinical data Health event/morbidity Health event/mortality Other Through organizations (health services or institutions schools businesses etc.) [10000-20000[ individuals Converting or copying information into a structured record Interview with the participant (including clinical) Observational Study Observational Study 16015 Unknown Restricted access Contact the principal investigator Access on specific project only