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<docDscr>
  <citation>
    <titlStmt>
      <titl>The French E3N Prospective Cohort Study</titl>
      <IDNo>FRESH-PEF3162-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="INSTITUT GUSTAVE ROUSSY (IGR)" role="">Camille LAPLANCHE</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
</docDscr>
<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                The French E3N Prospective Cohort Study            </titl>
      <altTitl>
                    E3N Study                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF3162-en            </IDNo>
      <IDNo agency="PEF">
                    3162                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF3162                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Marie-Christine BOUTRON-RUAULT                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="UNIVERSITE PARIS-SACLAY">
        <ExtLink title="ROR" URI="https://ror.org/03xjwb503" role="organisation id"/>
        <ExtLink title="SIREN" URI="130026024" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Gianluca SEVERI                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="UNIVERSITE PARIS-SACLAY">
        <ExtLink title="ROR" URI="https://ror.org/03xjwb503" role="organisation id"/>
        <ExtLink title="SIREN" URI="130026024" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="European EPIC study (European Prospective Investigation into Cancer and Nutrition)" type="collaboration">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            INSTITUT GUSTAVE ROUSSY (IGR)                    
                                    </producer>
      <producer role="sponsor">
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                    
                                    </producer>
      <producer role="sponsor">
                                            UNIVERSITE PARIS-SACLAY                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            EUROPEAN COMMISSION RESEARCH                    
                                    </fundAg>
      <fundAg>
                                            INSTITUT GUSTAVE ROUSSY (IGR)                    
                                    </fundAg>
      <fundAg>
                                            FONDATION ENTREPRISE MGEN SANTE PUBLIQUE (FSP MGEN)                    
                                    </fundAg>
      <fundAg>
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                    
                                    </fundAg>
      <fundAg>
                                            LIGUE NATIONALE CONTRE LE CANCER (LNCC)                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="UNIVERSITE PARIS-SACLAY" email="gianluca.severi@inserm.fr">
                    Gianluca;SEVERI
                                            <ExtLink title="ROR" URI="https://ror.org/03xjwb503" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="130026024" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-16"/>
      <distDate date="2026-06-16"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <topcClas vocab="cim-11">
                        COVID-19                                            </topcClas>
      <topcClas vocab="cim-11">
                        Malignant neoplasms of ill-defined or unspecified primary sites                                            </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants: Genetic predisposition                    </topcClas>
      <topcClas vocab="health determinant">
                        Environmental determinants: Other                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants: Use of care                    </topcClas>
      <topcClas vocab="health determinant">
                        Behavioral determinants: Eating habits                    </topcClas>
      <topcClas vocab="health determinant">
                        Socio-demographic and economic determinants: Employment                    </topcClas>
      <topcClas vocab="health determinant">
                        Environmental determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Socio-demographic and economic determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Biological determinants                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">Detecting risk factors of cancer and chronic pathologies in women</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="1990-01-01"/>
      <collDate event="end" date="2020-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">General population                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008875"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged (65 to 79 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000368"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged, 80 and over (80 years and more)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000369"/>
                                                    </universe>
      <universe clusion="I">Women born between 1925 and 1950 and affiliated with MGEN (Mutuelle Générale de l'Education nationale)                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Participant-reported health data</dataKind>
      <dataKind>Biological data</dataKind>
      <dataKind>Socio-demographic data</dataKind>
      <dataKind>Paraclinical data (non-biological) : Imaging</dataKind>
    </sumDscr>
    <qualityStatement>
      <standardsCompliance>
        <standard>
          <standardName>ICD 9 and ICD 10</standardName>
        </standard>
      </standardsCompliance>
    </qualityStatement>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality
Health care consumption and services
Quality of life/health perception</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Population database for statistical purposes</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>&gt;= 20000 individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Interview with the participant (including clinical)                                                            <concept vocab="CESSDA" vocabURI="Interview"/>
                                                    </collMode>
      <sources>
        <sources>
          <sourceCitation>
                                    
                                    
                                                                    </sourceCitation>
          <srcOrig>Medico-administrative database</srcOrig>
        </sources>
      </sources>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <notes subject="observational study method">
                        Cohort study                    </notes>
    <anlyInfo>
      <respRate>98 995</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <conditions>Data access methods for outside teams: authorization request to the scientific committee of the E3N study</conditions>
    </useStmt>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
</stdyDscr>
<dataDscr>
</dataDscr></codeBook>
