Epidemiological Study Concerning The Children of E3N Women FRESH-PEF3101-en Camille LAPLANCHE Epidemiological Study Concerning The Children of E3N Women E4N FRESH-PEF3101-en 3101 FRESH-PEF3101 Gianluca SEVERI INSTITUT GUSTAVE ROUSSY (IGR) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) UNIVERSITE PARIS-SACLAY Epidemiology France Portal (PEF) AGENCE NATIONALE DE LA RECHERCHE (ANR) null Gianluca;SEVERI family environment Lifestyle and behaviour family members family determinants COVID-19 Biological determinants: Genetic predisposition Environmental determinants: Other Healthcare system determinants: Use of care Behavioral determinants Behavioral determinants: Eating habits Socio-demographic and economic determinants: Employment Environmental determinants Socio-demographic and economic determinants Biological determinants Healthcare system determinants The familial E3N-E4N study purpose is to study health in relation to the modern way of life in people of the same family over three generations. The E4N study aims to extend the E3N study by following the descendants of women who participated in the E3N study. The objective is to better understand the onset of major diseases, from genetics, family environment and the environment outside the family. As well as gathering a large amount of prospective epidemiological data, E4N cohort permit the collection of important information concerning phenotypes and genetics. null France Individuals General population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) Women included in the E3N cohort (G1), Fathers of E3N women's children (G1) Sons and daughters of E3N women (G2), Grandchildren of E3N women (G3). Clinical data Participant-reported health data Biological data Socio-demographic data CIM 10 Health event/morbidity Health event/mortality Health care consumption and services Quality of life/health perception Other Population database for statistical purposes >= 20000 individuals Self-administered questionnaire Medico-administrative database Observational Study Observational Study Cohort study 18 000 fathers (E4N-G1) / 50 000 expected children (E4N-G2) / 20 000 expected grandchildren (E4N-G3) Unknown Metadata-only access Access on specific project only