A COhort to study BLAdder CancEr FRESH-PEF3096-en Maryam KARIMI A COhort to study BLAdder CancEr COBLAnCE FRESH-PEF3096-en 3096 FRESH-PEF3096 Maryam KARIMI INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) Epidemiology France Portal (PEF) AGENCE NATIONALE DE LA RECHERCHE (ANR) null Karine;GROUSSARD Maryam;KARIMI Bladder cancer urology cancer research cohort Oncology Diseases of the genitourinary system Behavioral determinants: Addiction Biological determinants: Genetic predisposition Behavioral determinants Behavioral determinants: Eating habits Healthcare system determinants: Use of care Socio-demographic and economic determinants: Employment Biological determinants Healthcare system determinants Socio-demographic and economic determinants 1) To test the association between constitutional DNA polymorphism, environmental parameters, molecular subtype and clinical data. The inclusion of features of both the tumour and the host will facilitate the discovery of tumourigenesis mechanisms, drugable targets and diagnostic and prognostic biomarkers. 2) To provide insight into the tumour progression knowledge and to help to identify biomarkers by the sequential sampling of recurrent tumors, plasma or urine from individual patients during follow_up. 3) To validate and extend our prior results regarding the molecular subtyping of bladder cancer on a large series of tumors collected prospectively. 4) To facilitate the transfer of study results into clinical practice thanks to the size and bladder cancer representativeness of the cohort. 5) To describe treatment patterns and to assess the direct and indirect costs of bladder cancer. The cost variability will be analyzed to identify the determinants of cost. This evaluation will pave the way for cost-benefit analyses of new biomarkers developed by the consortium. 6) To structure, at the national level, an interdisciplinary bladder cancer network including epidempiologists, bioinformaticians, health economists, molecular biologists, occupational physicians, pathologists and urologists, for coordinated and synergistic research actions and to make a significant contribution to a European multinational cohort and support international studies in genomics, in particular. null France Individuals Patients population Male Female Young Adult (19 to 24 years) Adult (25 to 44 years) Middle Aged (45 to 64 years) Aged (65 to 79 years) Aged, 80 and over (80 years and more) Inclusion as soon as possible after diagnosis of bladder cancer in the 17 participating hospitals Clinical data Participant-reported health data Biological data Socio-demographic data Health event/mortality Health care consumption and services Quality of life/health perception Others Other Through organizations (health services or institutions schools businesses etc.) [1000-10000[ individuals Self-administered questionnaire Medico-administrative database Observational Study Observational Study Cohort study 2000 patients Unknown Restricted access Access on specific project only