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<docDscr>
  <citation>
    <titlStmt>
      <titl>Incidence study with population of Rhone-Alpes region of cancers eligible for hadrontherapy by proton or carbon ions. Description of Tumors and patients characteristics</titl>
      <IDNo>FRESH-PEF2995-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="CENTRE LEON BERARD" role="">Pascal POMMIER</producer>
    </prodStmt>
    <verStmt>
      <version></version>
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  </citation>
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<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Incidence study with population of Rhone-Alpes region of cancers eligible for hadrontherapy by proton or carbon ions. Description of Tumors and patients characteristics            </titl>
      <altTitl>
                    EpiHadron                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF2995-en            </IDNo>
      <IDNo agency="PEF">
                    2995                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF2995                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Pascal POMMIER                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="CENTRE LEON BERARD">
        <ExtLink title="ROR" URI="https://ror.org/01cmnjq37" role="organisation id"/>
        <ExtLink title="SIREN" URI="779924133" role="organisation id"/>
      </AuthEnty>
      <AuthEnty>
                    Stéphanie PATIN                                                                                </AuthEnty>
      <AuthEnty affiliation="GROUPEMENT COOPERATION SANITAIRE CENTRE ETOILE">
        <ExtLink title="SIREN" URI="130004492" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="" type="">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            GROUPEMENT COOPERATION SANITAIRE CENTRE ETOILE                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            GROUPEMENT COOPERATION SANITAIRE CENTRE ETOILE                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="CENTRE LEON BERARD" email="pommier@lyon.fnclcc.fr">
                    Pascal;POMMIER
                                            <ExtLink title="ROR" URI="https://ror.org/01cmnjq37" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="779924133" role="organisation id"/>
                                    </contact>
      <depDate date="2026-06-17"/>
      <distDate date="2026-06-17"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    hadrontherapy</keyword>
      <keyword vocab="" vocabURI="">
                    descriptive prospective survey</keyword>
      <keyword vocab="" vocabURI="">
                    evaluation.</keyword>
      <keyword vocab="" vocabURI="">
                    Epidemiology</keyword>
      <keyword vocab="" vocabURI="">
                    incidence</keyword>
      <keyword vocab="" vocabURI="">
                    ENT</keyword>
      <topcClas vocab="health theme">
                        Oncology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/5784b7f1-c7ce-49d9-9f38-aebcda0ff41d"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D008495"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Otolaryngology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/9c3a57c5-68bd-4ee7-a9cc-aa8ba07bde94"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D010036"/>
                                                </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants: Use of care                    </topcClas>
      <topcClas vocab="health determinant">
                        Healthcare system determinants                    </topcClas>
    </subject>
    <abstract contentType="purpose">The main objective is to evaluate in the Rhône-Alpes region the incidence of cancers that have an indication eligible for treatment with hadrontherapy by proton or carbon ions.</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="2010-01-01"/>
      <collDate event="end" date="2012-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogCover>Auvergne Rhône-Alpes</geogCover>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">Patients population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Infant, Newborn (birth to 28 days)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D007231"/>
                                                    </universe>
      <universe level="age" clusion="I">Infant (28 days to 2 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D007223"/>
                                                    </universe>
      <universe level="age" clusion="I">Child, Preschool (2 to 5 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002675"/>
                                                    </universe>
      <universe level="age" clusion="I">Child (6 to 12 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002648"/>
                                                    </universe>
      <universe level="age" clusion="I">Young Adult (19 to 24 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D055815"/>
                                                    </universe>
      <universe level="age" clusion="I">Adult (25 to 44 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000328"/>
                                                    </universe>
      <universe level="age" clusion="I">Middle Aged (45 to 64 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008875"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged (65 to 79 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000368"/>
                                                    </universe>
      <universe level="age" clusion="I">Aged, 80 and over (80 years and more)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D000369"/>
                                                    </universe>
      <universe clusion="I">Type of tumors to identify: A list of the main indications for hadrontherapy by protons and by carbon ions (Appendix 1: list of indications) was developed by experts using data from literature prioritized according to an ""evidence based medicine"" type analysis and based on rendered or expected service criteria (survival and quality of life), (Appendix 2: Literature review method).   Criteria for ""patient"" inclusion The study will be carried out with adult and child subjects, with no age limit, who have indications of hadrontherapy, whose dossiers were able to be discussed by experts at a preliminary pluridisciplinary concertation meeting (RCP).  Subjects must have a general and psychological condition that is compatible with hadrontherapy (good compliance, possible follow-up, accept to travel where applicable) and absence of co-morbidities that are life-threatening.   Criteria for ""tumor"" inclusion The characteristics common to the pathologies to be identified are as follows:  Inoperable tumors, which belong to a pathological group recognized as radio-resistant, at the early stage of development (locoregional stage) or recurring or local relapse, with a low metastatic potential or with an M+ dissemination controlled by medical treatments.                      </universe>
      <universe clusion="E">Tumors: Choroidal melanomas are excluded from the study. Patients: General or psychological condition that is not compatible or threatening co-morbidities.                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Biological data</dataKind>
      <dataKind>Socio-demographic data</dataKind>
    </sumDscr>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health care consumption and services
Others</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Through organizations (health services or institutions</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>schools</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>businesses</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>etc.)</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>[500-1000[ individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <anlyInfo>
      <respRate>800</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
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