Registry of Congenital Malformations in Auvergne (Certified Registry 2012-2015) FRESH-PEF230-en Isabelle PERTHUS Registry of Congenital Malformations in Auvergne (Certified Registry 2012-2015) CEMC-Auvergne FRESH-PEF230-en 230 FRESH-PEF230 Isabelle PERTHUS CENTRE HOSPITALIER UNIVERSITAIRE DE CLERMONT-FERRAND Epidemiology France Portal (PEF) INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) SANTE PUBLIQUE FRANCE AGENCE REGIONALE DE SANTE null Isabelle;PERTHUS prenatal diagnosis Paediatrics Developmental anomalies Behavioral determinants: Addiction Biological determinants: Genetic predisposition Healthcare system determinants: Use of care Behavioral determinants Socio-demographic and economic determinants: Employment Biological determinants Healthcare system determinants Socio-demographic and economic determinants The registry's primary objective is to conduct epidemiological surveillance of congenital malformations in Auvergne, with a role of sounding the alert when any environmental teratogenic agents become evident. With the development of prevention measures - particularly in the field of prenatal diagnosis - this surveillance-alert mission has gradually been extended to include an essential role in evaluating the impact of public health policies with regards to perinatal care on the population. The registry also helps to improve knowledge in the field of malformations by collaborating on studies with specialist clinical departments (particularly genetic and foetal medicine departments) and by being involved in the Multidisciplinary Center for Prenatal Diagnosis in Clermont- Ferrand (the registry's data provides food for thought from obstetricians on the meaning and action to take when certain malformations are observed during prenatal diagnosis). Lastly, the registry's data informs healthcare stakeholders and the public authorities about congenital malformations and chromosomal abnormalities. null France Auvergne Rhône-Alpes Individuals People with disabilities Male Female Infant, Newborn (birth to 28 days) Infant (28 days to 2 years) All malformed children are listed, whether stillborn or a live birth after a pregnancy of at least 22 weeks of amenorrhoea, or in the event of therapeutic abortion due to foetal malformation, regardless of term. For children who are born alive, the malformation diagnosis must have been made before the end of their first year of life (infants may be recorded up to 12 months after their birth). All types of malformation are included, whether these concern isolated or polymalformative syndromes, whether or not identified, with normal or abnormal karyotype. are inborn metabolic errors and minor malformations or deformations (snapping hips without real dislocation, deformed feet, small superficial naevi or angiomas less than 4cm2, inguinal hernia, umbilical hernia not requiring surgery, isolated persistent ductus arteriosus in premature infants weighing less than 2.5kg, hypertrophic pyloric stenosis, single umbilical artery, uni- or bilateral ectopic testis). Clinical data Biological data Socio-demographic data Paraclinical data (non-biological) : Imaging ICD 10 ATC. Health event/morbidity Health event/mortality Other [10000-20000[ individuals Other Observational Study Observational Study Morbidity registry 10 145 patients (1983-2011) Unknown Restricted access By request to the scientist in charge. Access on specific project only