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  <citation>
    <titlStmt>
      <titl></titl>
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        <_value></_value>
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<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Register of Childhood Disabilities and Perinatal Data - Isère et deux Savoie counties            </titl>
      <altTitl>
                    RHEOP                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF168-en            </IDNo>
      <IDNo agency="PEF">
                    168                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF168                </IDNo>
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    <rspStmt>
      <AuthEnty>
                    Christine CANS                                                                                                                                                            <ExtLink title="IdRef" URI="100952798" role="pi id"/>
                                                        </AuthEnty>
      <AuthEnty affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE GRENOBLE">
        <ExtLink title="ROR" URI="https://ror.org/041rhpw39" role="organisation id"/>
        <ExtLink title="SIREN" URI="263800302" role="organisation id"/>
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      <othId affiliation="" type="">
                                    </othId>
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    <prodStmt>
      <producer role="sponsor">
                                            DEPARTEMENT DE L ISERE                                            <ExtLink title="SIREN" URI="223800012" role="sponsor id"/>
                    
                </producer>
      <producer role="sponsor">
                                            DEPARTEMENT DE LA SAVOIE                                            <ExtLink title="SIREN" URI="227300019" role="sponsor id"/>
                    
                </producer>
      <producer role="sponsor">
                                            DEPARTEMENT DE LA HAUTE SAVOIE                                            <ExtLink title="SIREN" URI="227400017" role="sponsor id"/>
                    
                </producer>
      <producer role="sponsor">
                                            UNIVERSITE GRENOBLE ALPES                                            <ExtLink title="ROR" URI="https://ror.org/02rx3b187" role="sponsor id"/>
                                            <ExtLink title="SIREN" URI="130026081" role="sponsor id"/>
                    
                </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            DEPARTEMENT DE L ISERE                                            <ExtLink title="SIREN" URI="223800012"/>
                                    </fundAg>
      <fundAg>
                                            DEPARTEMENT DE LA HAUTE SAVOIE                                            <ExtLink title="SIREN" URI="227400017"/>
                                    </fundAg>
      <fundAg>
                                            DEPARTEMENT DE LA SAVOIE                                            <ExtLink title="SIREN" URI="227300019"/>
                                    </fundAg>
      <fundAg>
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                                            <ExtLink title="ROR" URI="https://ror.org/02vjkv261"/>
                                            <ExtLink title="SIREN" URI="180036048"/>
                                    </fundAg>
      <fundAg>
                                            SANTE PUBLIQUE FRANCE                                            <ExtLink title="ROR" URI="https://ror.org/00dfw9p58"/>
                                            <ExtLink title="SIREN" URI="130022338"/>
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="" email="">
                    
                                    </contact>
      <depDate date="2026-10-15"/>
      <distDate date="2026-10-15"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <studyAuthorization>
    <authorizingAgency>CNIL                </authorizingAgency>
  </studyAuthorization>
  <stdyInfo>
    <studyBudget/>
    <subject>
      <keyword vocab="" vocabURI="">
                    Stillbirth and Induced therapeutic abortions Severe deficiencies of the child</keyword>
      <topcClas vocab="health theme">
                        Gynaecology and obstetrics                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/7de64596-5b0d-4977-8f98-b982ff2ec17d | http://data.europa.eu/8mn/euroscivoc/284ca20c-beb4-4abe-99fa-ef4513358bad"/>
                                                            <ExtLink title="MeSH" URI="D006176 | D009774"/>
                                                </topcClas>
      <topcClas vocab="health theme">
                        Paediatrics                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/bf8aaaac-ddee-41cd-bb8a-c5a63de3fcbd"/>
                                                            <ExtLink title="MeSH" URI="D010372"/>
                                                </topcClas>
    </subject>
    <abstract contentType="purpose">In the area of public health: (1) monitor the change in the prevalence of severe deficiencies in children on a geographical basis (three counties starting in 2005) (2) monitor the change in the rate of stillbirths and more particularly of the prevalence of induced abortions for medical reasons over the same geographical base (3) describe the educative and medical care (4) assist in the planning of needs, in order to ensure optimal care for these children In the area of research: (1) encourage analytical surveys that are specific to each type of deficiency, or that cover the associated deficiencies (2) identify the etiologies of the deficiencies and serious perinatal events (3) Collect information on the perinatal events that may be in relation with the occurence of deficiencies</abstract>
    <abstract contentType="abstract">null</abstract>
    <sumDscr>
      <collDate event="start" date="1991-01-01"/>
      <nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation>
      <geogCover>Auvergne Rhône-Alpes</geogCover>
      <geogUnit/>
      <anlyUnit>
                Individuals            </anlyUnit>
      <universe level="type" clusion="I">Patients population                    </universe>
      <universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="D008297"/>
                                                    </universe>
      <universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="D005260"/>
                                                    </universe>
      <universe level="age" clusion="I">Infant, Newborn (birth to 28 days)                                                            <concept vocab="MeSH" vocabURI="D007231"/>
                                                    </universe>
      <universe level="age" clusion="I">Infant (28 days to 2 years)                                                            <concept vocab="MeSH" vocabURI="D007223"/>
                                                    </universe>
      <universe level="age" clusion="I">Child (6 to 12 years)                                                            <concept vocab="MeSH" vocabURI="D002648"/>
                                                    </universe>
      <universe clusion="I">Deficiency pool: All children under the age of 7 years having at least one main severe deficiency and residing in one of the départements of Isère, Savoie or Haute-Savoie.  Perinatal pool: serious perinatal events such as cases of stillbirth and abortion occurring each year for the women domiciled in one of these three départements.                    </universe>
      <dataKind>Clinical data</dataKind>
      <dataKind>Socio-demographic data</dataKind>
    </sumDscr>
  </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality
Health care consumption and services
Quality of life/health perception</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <targetSampleSize>
        <sampleSizeFormula>[1000-10000[ individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Converting or copying information into a structured record                                                            <concept vocab="CESSDA" vocabURI="Transcription"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <notes subject="observational study method">
                        Morbidity registry                    </notes>
    <anlyInfo>
      <respRate>2717 : several deficiency 2414 : stillbirths 2317 : medical termination of pregnancy</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
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      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
  </dataAccs>
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    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
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<dataDscr>
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